Changing Signals - inaugural lecture from Professor Pietro Ghezzi
Published 22 October 2009
Event 24 November 2009
Exploring repair mechanisms for brain inflamation
Cytokines are proteins that signal the presence of infection to the various cells of the immune system. It was first biochemistry, then genetic engineering, applied to immunology that led to the discovery of these signals. More research into these molecules led to the unexpected finding that many cytokines can be harmful, and responsible for several inflammatory diseases.
Understanding the cytokine network has become more and more complex, by the discovery of new cytokines and further knowledge of the new activities of known cytokines. At the same time, some cytokines and their inhibitors have become approved drugs. It is now clear that these mechanisms and signals are not only important in infection and immunity, but also play a role in the response to injury and promote repair.
Professor Ghezzi will give an overview of the discovery of these signals, how they regulate each other and how can switch from defending from infections to causing diseases or inducing repair. In particular, the talk will focus on how the discovery of the protective and repairing abilities of some cytokines is leading to therapeutic strategies targeting brain inflammation, an avenue to the cure of diseases such as stroke and multiple sclerosis.
Changing Signals: exploring repair mechanisms for brain inflammation
Pietro Ghezzi
RM Phillips Chair of Experimental Medicine
Tuesday 24 November 2009 at 6.30pm
Chowen lecture theatre
Brighton and Sussex Medical School
University of Sussex
Falmer BN1 9PX
Light refreshments will be served after the lecture.
All welcome - if you would like to attend please email events@brighton.ac.uk.
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