Dr Angela Sheerin
Senior Research Fellow
contact:
Pharmacy and Biomolecular Sciences
Moulsecoomb
Brighton
BN2 4GJ
Telephone: +44 (0)1273 641032
Email: A.N.Sheerin@brighton.ac.uk
Research Interests
- Cell Biologist
- Gerontology
- Senescence and lifespan
- Occular Biology
- Differentiation Pathways
- Occular Age-related disorders
Recent Publications
Sheerin, A, Smith, S.K., Jennert-Burston, K., Brook, A.J., Allen, M.C., Ibrahim, B., Jones , D.L., Wallis , C, Engelmann, K, Rhys-Williams, W, Faragher, R.G.A. and Kipling, D. (2012) Characterization of cellular senescence mechanisms in human corneal endothelial cells Aging Cell, 11 (2). pp. 234-240. ISSN 1474-9718
Faragher, R.G.A., Burton, D, Majecha, P., Fong, N.S., Davis, T, Sheerin, A and Ostler, E.L. (2011) Resveratrol, but not dihydroresveratrol, induces premature senescence in primary human fibroblasts AGE, 33 (4). pp. 555-564. ISSN 0161-9152
Burton, D.J., Giles, P.J., SHEERIN, ANGELA, Smith, S.K., Lawton, J.J., OSTLER, ELIZABETH, Rhys-Williams, W, Kipling, D. and FARAGHER, RICHARD (2009) Microarray analysis of senescent vascular smooth muscle cells: a link to atherosclerosis and vascular calcification Experimental Gerontology, 44 (10). pp. 659-665. ISSN 0531-5565
Faragher, R.G.A., Sheerin, A. and Ostler, E.L. (2009) Can we intervene in human ageing? Expert Reviews in Molecular Medicine, 11 (e27). ISSN 1462-3994
Burton, D, Sheerin, A, Ostler, E.L, Smith, K, Giles, P.J, Lowe, J, Rhys-Williams, W, Kipling, D.G and Faragher, R.G.A (2007) Cyclin D1 over-expression permits the reproducible detection of senescent human vascular smooth muscle cells Annals of the New York Academy of Sciences, 1119 . pp. 20-31. ISSN 1-57331-686-5
Lowe, J., Sheerin, A., Jennert-Burston, K., Burton, D., Ostler, E.L., Bird, J., Green, M.H.L. and Faragher, R.G.A. (2004) Camptothecin sensitivity in Werner syndrome fibroblasts as assessed by the COMET technique Annals of the New York Academy of Sciences, 1019 . pp. 256-259. ISSN 1749-6632
Wallis, C.V, SHEERIN, ANGELA, Green, M.H.L., Jones, C.J., Kipling, D. and FARAGHER, RICHARD (2004) Fibroblast clones from patients with Hutchinson–Gilford progeria can senesce despite the presence of telomerase Experimental Gerontology, 39 (4). ISSN 0531-5565
Sheerin, A, Thompson, K.S.J and Goyns, M.H (2002) Altered composition of the AP-1 transcription factor in immortalized compared to normal proliferating cells Cancer Letters, 177 (1). pp. 83-87. ISSN 0304-3835
OSTLER, ELIZABETH, Wallis, C.V, SHEERIN, ANGELA and FARAGHER, RICHARD (2002) A model for the phenotypic presentation of Werner's syndrome Experimental Gerontology, 37 (2-3). ISSN 0531-5565
Sheerin, A, Thompson, K.S.J and Goyns, M.H (2001) Altered composition and DNA binding activity of the AP-1 transcription factor during the ageing of human fibroblasts Mechanisms of Ageing and Development, 122 (15). pp. 1813-1824. ISSN 0047-6374


