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Dr Jonathan Salvage

Research Fellow

contact:
Pharmacy and Biomolecular Sciences
Moulsecoomb
Brighton
BN2 4GJ

Email: J.P.Salvage@brighton.ac.uk

Research interests

  • Imaging and analysis of nanomaterials, applying scanning electron microscopy (SEM), scanning transmission electron microscopy (STEM), and atomic force microscopy (AFM) technologies.
  • The effects of particle composition and size, upon cellular interactions influencing the uptake and distribution of nanoparticles, employing in-vitro cell assays and confocal microscopy (CLSM).
  • Investigating size and polydispersity shifts in polymeric nanoparticle systems in response to compositional and environmental changes, utilising Photon Correlation Spectroscopy (PCS).
  • The influence of particle composition on the loading potential of the systems, for drug delivery and cell imaging applications.

Teaching and scholarly activities

The Image and Analysis Unit [IAU]
Academic Lead for the Image and Analysis Unit with responsibility for undergraduate, postgraduate, and postdoctoral teaching, training, and support in the use of:

  • Scanning electron microscopy (SEM) – high vacuum and environmental
  • Scanning transmission electron microscopy (STEM)
  • Energy dispersive X-Ray spectroscopy (EDS)
  • Cryo-SEM
  • Atomic force microscopy (AFM)
  • Confocal laser scanning microscopy (CLSM) and fluorescence microscopy
  • Photo correlation spectroscopy (PCS) and (DLS)
  • Contact angle measurement (OCA) of material surfaces

Undergraduate

BSc(Hons) Biological Sciences and BSc(Hons) Biomedical Science degree courses

  • Academic Tutoring
    • BY131 Practical Skills in BioSciences
    • BY299 Biology Professional and Career Development
  • Final Year Project and Dissertation Supervisor

Postgraduate

MRes Pharmaceutical and Biomedical Sciences – Master of Research degree course

  • Module leadership
    • PBM12 Bioanalytical techniques for pharmaceutical and biomedical sciences
    • PBM11 Analytical techniques for pharmaceutical and biomedical sciences

Committee membership

Member of the University of Brighton Biology and Biomedical Science Divisional Board

Professional memberships

Member of the Royal Microscopical Society (RMS)
Member of the European Microscopy Society (EMS)

Quorum Technologies Prize Scheme

Co-ordinates the Quorum Technologies Prize Scheme collaboration between The Image and Analysis Unit, University of Brighton, and Quorum Technologies Ltd, to promote and support excellence in electron microscopy amongst undergraduate and postgraduate students.

Refereeing

Referee for The Journal of Materials Science: Materials in Medicine

Patents

Co-inventor of a novel application of soybean derived biodegradable biomaterials

  • Bioactive and resorbable soy-based biomaterials (2009). International Patent Application Publication: WO/2009/068913.

Co-inventor of a novel polymeric self-assembling biomimetic nanoparticulate drug delivery system

  • Drug carriers comprising amphiphilic block copolymers (2003). International Patent Application Publication: WO/03/074026 A1.

Recent Publications

Number of items: 9.

MEIKLE, STEVE, STANDEN, GUY, SALVAGE, JONATHAN, De Santis, Roberto, Nicolais, Luigi, Ambrosio, Luigi and SANTIN, MATTEO (2012) Synthesis and characterization of soybean-based hydrogels with an intrinsic activity on cell differentiation Tissue Engineering: Parts A, B, and C, 18 (17-18). ISSN 1937-3368

Karabanova, Lyuda, WHITBY, RAYMOND, Korobeinyk, Alina, Bondaruk, Oksana, SALVAGE, JONATHAN, LLOYD, ANDREW and MIKHALOVSKY, SERGEY (2012) Microstructure changes of polyurethane by inclusion of chemically modified carbon nanotubes at low filler contents Composites Science And Technology, 72 (8). ISSN 0266-3538

Korobeinyk, Alina, WHITBY, RAYMOND, SALVAGE, JONATHAN and MIKHALOVSKY, SERGEY (2012) Exfoliated production of single- and multi-layer graphenes and carbon nanofibres from the carbonisation of a co-polymer Carbon, 50 (5). ISSN 0008-6223

Perut, F., Montufar, E.B., Ciapetti, G., Santin, M., Salvage, J.P., Traykova, T., Planell, J.A., Ginebra, M.P. and Baldini, N. (2010) Novel soybean/gelatine-based bioactive and injectable hydroxyapatite foam: material properties and cell response Acta Biomaterialia , 7 (4). pp. 1780-1787. ISSN 1742-7061 (In Press)

Giavaresi, G., Fini, M., Salvage, J.P., Aldini, N.N., Giardino, R., Ambrosio, L., Nicolais, L. and Santin, M. (2009) Bone regeneration potential of a soybean-based filler: experimental study in a rabbit cancellous bone defects Journal of Materials Science: Materials in Medicine, 21 (2). pp. 615-626. ISSN 0022-2461

Salvage, J.P., Rose, S.F., Phillips, G.J., Hanlon, G.W., Lloyd, A.W., Ma, I.Y., Armes, S.P., Billingham, N.C. and Lewis, A.L. (2005) Novel biocompatible phosphorylcholine-based self-assembled nanoparticles for drug delivery Journal of controlled release, 104 (2). pp. 259-270. ISSN 0168-3659

West, S.L., Salvage, J.P., Lobb, E.J., Armes, S.P., Billingham, N.C., Lewis, A.L., Hanlon, G.W. and Lloyd, A.W. (2004) The biocompatibility of crosslinkable copolymer coatings containing sulfobetaines and phosphobetaines Biomaterials, 25 (7-8). pp. 1195-1204. ISSN 0142-9612

Ma, Y.H., Tang, Y.Q., Billingham, N.C., Armes, S.P., Lewis, A.L., Lloyd, A.W. and Salvage, J.P. (2003) Well-defined biocompatible block copolymers via atom transfer radical polymerization of 2-Methacryloyloxyethyl Phosphorylcholine in protic media Macromolecules, 36 (10). pp. 3475-3484. ISSN 0024-9297

Ma, I.Y., Lobb, E.J., Billingham, N.C., Armes, S.P., Lewis, A.L., Lloyd, A.W. and Salvage, J.P. (2002) Synthesis of biocompatible polymers. 1. homopolymerization of 2-Methacryloyloxyethyl Phosphorylcholine via ATRP in protic solvents: an optimization study Macromolecules, 35 (25). pp. 9306-9314. ISSN 0024-9297

This list was generated on Sat Jan 12 16:09:25 2013 GMT.