Dr Lesley Ogilvie
Senior Research Fellow
contact:
Pharmacy and Biomolecular Sciences
Moulsecoomb
Brighton
BN2 4GJ
Email: L.Ogilvie@brighton.ac.uk
Research Interests
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Microbes and cancer
The role of microbial bile salt hydrolase activity in the development of colorectal cancer
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Microbial ecology
Using functional metagenomic approaches to explore the genetic and metabolic diversity of microbial communities within natural environments
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Microbial ecological theory
Defining and developing a theoretical framework for interpretation of laboratory and field observations
Publications (2008 - present)
OGILVIE, LESLEY, CAPLIN, JONATHAN, DEDI, CYNTHIA, Diston, D., CHEEK, LIZ, Bowler, L., TAYLOR, HUW, EBDON, JAMES and JONES, BRIAN (2012) Comparative (meta)genomic analysis and ecological profiling of human gut specific bacteriophage B124-14 PLoS ONE, 7 (4). ISSN 1932-6203
Ogilvie, L.A. and Jones, B.V. (2012) Dysbiosis modulates capacity for bile acid modification in the gut microbiomes of patients with inflammatory bowel disease: a mechanism and marker of disease? GUT . ISSN 1468-3288
JONES, BRIAN and OGILVIE, LESLEY (2012) Evolutionary, ecological and biotechnological perspectives on plasmids resident in the human gut mobile metagenome Bioengineered Bugs, 3 (1). pp. 13-31. ISSN 1949-1018
Ogilvie, L.A., Overall, A.D.J. and Jones, B.V. (2012) The human-mirobiome co-evolutionary continuum In: Ogilvie, L.A. and Hirsch, P., eds. Microbial ecological theory: current perspectives. Caister Academic Press . ISBN 9781908230096
Dietrich, M., Bartfeld, S., Munke, R., Lange, C., Ogilvie, L.A., Friedrich, A. and Meyer, T.F. (2011) Activation of NF-κB by Neisseria gonorrhoeae is associated with microcolony formation and type IV pilus retraction Cellular Microbiology, 13 (8). pp. 1168-1182. ISSN 1462-5814
Fassi Fehri , L., Mak, T.N., Laube, B., Brinkmann, V., Ogilvie, L.A., Mollenkopf, H., Lein, M., Schmidt, T., Meyer, T.F. and Brüggemann, H. (2011) Prevalence of Propionibacterium acnes in diseased prostates and its inflammatory and transforming activity on prostate epithelial cells International Journal of Medical Microbiology, 309 (1). pp. 69-78. ISSN 1438-4221
Ogilvie, L.A. and Hirsh, P., eds. (2011) Microbial Ecological Theory: from individuals to ecosystems Horizon Press, Norwich, UK, pp. 211-216. (In Press)
Sörensen, M., Mak, T.N., Hurwitz, R., Mollenkopf, H., Ogilvie, L.A., Meyer, T.F. and Brüggemann, H. (2010) Mutagenesis of Propionibacterium acnes and analysis of two CAMP factor knock-out mutants Journal of Microbiological Methods, 83 (2). pp. 211-216. ISSN 0167-7012
Bartfeld, S., Hess, S., Bauer, B., Machuy, N., Ogilvie, L.A., Schuchhardt, J. and Meyer, T.F. (2010) High-throughput and single-cell imaging of NF-kappaB oscillations using monoclonal cell lines BMC Cell Biology, 11 (21). ISSN 1471-2121
Ogilvie, L.A., Heuer , D. and Meyer, T.F. (2010) Chlamydia: from molecular insight to therapeutic discovery In: Sansonetti , P., ed. Bacterial virulence: Basic Principles, Models and Global Approaches. Wiley-VCH, Weinheim, pp. 165-182.
Karlas, A., Machuy, N., Shin, Y., Pleissner, K.P., Artarini, A., Heuer , D., Becker, D., Khalil, H., Ogilvie, L.A., Hess, S., Mäurer, A.P., Müller, E., Wolff, T., Rudel, T. and Meyer, T.F. (2010) Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication Nature, 463 (7282). pp. 818-822. ISSN 0369-3392
Ogilvie, L.A. and Hirsh, P. (2010) Microbial diversity: Methods and meaning. In: Trepper, G.H., ed. Species Diversity and Extinction. Nova Science Publishers, New York, USA. (In Press)
Ogilvie, L.A., Hirsch, P. and Johnston, A.W. (2008) Bacterial diversity of the broadbalk 'classical' winter wheat experiment in relation to long-term fertilizer inputs Microbial Ecology, 56 (3). pp. 525-537. ISSN 0095-3628
Ogilvie, L.A. and Grant, A. (2008) Linking pollution induced community tolerance (PICT) and microbial community structure in chronically metal polluted estuarine sediments Marine Environmental Research, 65 (2). pp. 187-198. ISSN 0141-1136
Johnston, A.W.B., Li, Y. and Ogilvie, L.A. (2005) Metagenomic marine nitrogen fixation – feast or famine? Trends in Microbiology, 13 (9). pp. 416-420. ISSN 0966-842X
Grant, A. and Ogilvie, L.A. (2004) Name that microbe: Rapid identification of taxa responsible for individual fragments in T-RFLP, LH-PCR and ARISA fingerprints of microbial community structure Molecular Ecology Notes, 4 (1). pp. 133-136. ISSN 1471-8278
Grant, A. and Ogilvie, L.A. (2003) Terminal restriction fragment length polymorphism data analysis Applied and Environmental Microbiology, 69 (10). pp. 6342-6343. ISSN 0099-2240


