Skip to content

Dr Paul Gard

Assistant Head of School/Reader

contact:
Pharmacy and Biomolecular Sciences
Moulsecoomb
Brighton
BN2 4GJ

Telephone: +44 (0)1273 642084

Email: P.R.Gard@brighton.ac.uk

Research Interests

  • Effects of hormones on mood and behaviour
  • Use of medicines in paediatric populations
  • Counterfeit medicines

Scholarly Activities

Scholarships and Awards

SERC. Research Studentship, Department of Pharmacy, University of Aston in Birmingham, (1979-1982)
Wellcome Trust Travel Grant (Sept. 1984) to visit the Departments of Psychiatry and Obstetrics & Gynecology, YALE UNIVERSITY, U.S.A.
The British Council Travel Grant (July 1994) to visit the Department of Psychiatry, UNIVERSITY OF MONTREAL. Canada.
Merck-DuPont Travel Award (January 1999): to attend the International Forum on Angiotensin II Receptor Antagonists, Monte Carlo
Merck-DuPont Travel Award (January 2000): to attend the 3rd International Symposium on Angiotensin II Antagonism, London

Postitions of responsibility

1989 Stage II course leader in pharmacology, NZ School of Pharmacy
1994-2001 Department of Pharmacy Publicity Coordinator
1996- Examinations Officer, BSc/MPharm (Hons) Pharmacy
2002- Course Leader, MPharm (Hons) Pharmacy
2002- Pharmacology Discipline Leader, Brighton and Sussex Medical School

Postgraduate Research (PhD) Supervision

J.S. Malhi PhD (Awarded 1991) Thesis title: Some Factors Affecting the Microbial Status of the Mammalian Uterus.
J.P. Reynolds PhD (Awarded 1995) Project title: Development of a Novel Means of Drug Delivery to the Female Genital Tract.
A. Mandy PhD (Awarded 1996) Project title: The Role of Angiotensin in The Aetiology of Post-Partum Depressive Disorders.
N.M. Tyers PhD (Awarded 1996) Project title: Effects of Dietary Components upon Breast Cell Physiology
S.N. Ostad PhD (Awarded 1996) Project title: Investigation of Toxicological and Teratogenic Effects of Drugs Delivered to the Genital Tract.
T. Pountney PhD (Awarded 2002) Project title: The effectiveness of postural management programmes in the reductuction of hip dislocation and spinal curvature in children with cerebral palsy.
O. Al-Omran PhD (Awarded 2002) Project title: Factors affecting adherence to medication in school children.
A. El-Modani PhD (1997- ) Project title: In vitro modelling of the factors affecting drug delivery to the male genitourinary tract.
D. Bakheet PhD (1999- ) Project title: The role of angiotensin related polymorphisms in the aetiology of hypertension in a Saudi population.
N. Ali MPhil/PhD (1999- ) Age-induced changes in serotonergic system – new insights in to the processes of normal ageing.
M. Burn MPhil/PhD (2001- ) The role of purine receptors in mucus secretion in sheep tracheal explants.
Y. Saab MPhil/PhD (2001- ) Genetic polymorphisms of the renin-angiotensin system and their relationship with psychological disorders

Committee Membership

Pharmacy Board of Study (1983-98)
Pharmaceutical Sciences Research Group Management Team (1986-1992)
Nursing Studies Board of Examiners (1983-1990)
Pharmacy Board of Examiners (1983- )
Pharmacy Course Review Sub-Committee (1983-1990)
Pharmacy BSc Honours Course Validation Committee (1988 & 1993)
Faculty Research Committee (1997-8 )
Pharmacy Staff Student Committee (1983- ; Chair 1995-2001)
Pharmacy Information Technology Committee (1992- )
Pharmacy Divisional Management Group, Secretary (1998 – )
MPharm Course Board (1998 – , Chair 2002 -)
Pharmacy Divisional Board (1998 – )
School Board, School of Pharmacy and Biomolecular Sciences (1998 – )
Faculty Board, Faculty of Science and Engineering (1998 – 2001)
University Academic Health Working Group (A sub-group of Academic Board) (1999–2001)
School of Pharmacy & Biomolecular Sciences Ethics Committee (Chair, 2000 - )
University Animal Ethics Committee (2001 - )
MPharm Course Development Team (Chair, 2001 - )

Module Leadership

1997- Essential Biology (MPharm Level 1)
Introduction to personal skills and social factors in pharmacy (MPharm Level 1)
Principles of anatomical structure, physiological function and drug action (MPharm Level 1)
Laboratory studies in cell physiology and drug action (MPharm Level 1)
Growth and metabolism (MPharm Level 2)
1998- Basic and Applied Pharmacology (Modular Science Scheme, Level 2).
Information Retrieval and Presentation (MPharm Level 2)
2000- Experimental Design and Analysis (MPharm Level 2)
2002- Heart, Lung and Blood, Brighton and Sussex Medical School.

External Examining

External Examiner, B.Pharm., School of Pharmacy, University of London, 1992-1994
External Examiner, BSc (Hons) Bioscience and Health; BSc (Hons) Human Biology, BSc (Hons) Health Studies, Leeds Metropolitan University, 1996- , Chief Examiner 1998- 2000
External Examiner, PhD; School of Pharmacy, Monash University, Melbourne, Australia (1997)
External Examiner, PhD; School of Pharmaceutical Sciences, University of Aston in Birmingham (1999)
External Examiner, PhD; Welsh School of Pharmacy, Cardiff University (2000)
External Examiner, PhD; Welsh School of Pharmacy, Cardiff University (2000)
External Examiner, PhD; Department of Pharmacy and Chemistry, Liverpool John Moore's University (2002)
External Examiner, PhD; Welsh School of Pharmacy, Cardiff University (2003)

Society Memberships

British Pharmacological Society
British Neuroscience Association
International Brain Research Organisation

Affiliations

Industrial Consultancies

Dista Products Limited (1982)
Ciba Laboratories (1987-1988)
Delandale Laboratories (1987-1989)
G.D. Searle (1990-1993)
Martin Biggs Associates (1985-93)

External Advisory Service

Invited Member, Royal Pharmaceutical Society of Great Britain Working Party on 'The Introduction of Behavioural Sciences into the Undergraduate Pharmacy Course', 1989
Grant referee, New Zealand Lottery Grant Board, 1990
Grant referee, The Wellcome Trust, 1994
Grant referee and Member, Royal Pharmaceutical Society of Great Britain Practice Research Awards Panel (1994)
Grant referee, Royal Pharmaceutical Society of Great Britain Science Research Awards Panel (1998)
Member, University of Sussex Human Ethics Commitee, (1996- )
Scientific Reviewer, Current Drugs Weekly/Investigational Drugs Database (1997-2001)
External Research Advisor, Health and Social Research Grants Programme (Community Fund), National Lotteries Charities Board. (1998 - )
Co-Opted Member, Academic Pharmacists Group Committee, General Pharmaceutical Council (GPhC) GB (2001- )

Conferences and Meetings Organised/Chaired

Assistant Course Organiser, SE & SW Thames Regions of Royal Pharmaceutical Society of Great Britain Residential Continuing Education Courses, 1984-1988
Conference Organiser: 3-day workshop on the teaching of behavioural sciences in undergraduate pharmacy courses, Brighton, July 1988
Invited Chairman, Oral presentation session on 'Antidepressant drugs in animal models', IUPHAR XIth International Congress of Pharmacology, Amsterdam, 1990
Invited Chairman, Oral presentation session on 'Pharmacokinetics and Drug Metabolism', European Federation of Pharmaceutical Science, International Congress of Pharmaceutical Sciences, Edinburgh, 1996
Conference Organiser, Royal Pharmaceutical Society Schools of Pharmacy Easter Conference, Brighton, 2004

Research Publications

Number of items: 35.

Gard, P.R., Naylor, C., Sofiya, A. and Partington, C. (2012) Blockade of pro-cognitive effects of angiotensin IV and physostigmine in mice by oxytocin antagonism European Journal of Pharmacology, 683 . pp. 155-160. ISSN 0014-2999

Saab , Y.B., Gard , P.R. and Overall, A.D.J. (2011) The association of hypertension with renin-angiotensin system gene polymorphisms in the Lebanese population Journal of the Renin-Angiotensin-Aldosterone System, 12 (7). pp. 588-594. ISSN 1470-3203

Mechaeil, R., Gard, P.R., Jackson, A. and Rusted, J. (2011) Cognitive enhancement following acute losartan in normotensive young adults Psychopharmacology, 217 (1). pp. 51-60. ISSN 0033-3158

Gard, P.R., Olivier, G.W.J., Golding, B., Bourner, C., Dang, T., Haliru, H., Higgins, E., Kimberley, H., Loginova, O., Madhavi, S. and Ryan, D. (2011) Assessment of biological activity of novel peptide analogues of angiotensin IV Journal of Pharmacy & Pharmacology, 63 (4). pp. 565-571. ISSN 0022-3573

Golding, B.J., OVERALL, ANDREW and GARD, PAUL (2011) Strain differences and the role of AT1 receptor expression in anxiety International Journal of Molecular Epidemiology and Genetics, IJMEG, 2 (1). pp. 51-55. ISSN 1948-1756

Demaegdt, H., Gard, P.R., De Backer, J-P., Lukaszuk, A., Szemenyei, E., Toth, G., Tourwe, D. and Vauquelin, G. (2011) Binding of AT4 receptor ligands to insulin regulated aminopeptidase (IRAP) in intact Chinese hamster ovary cells Molecular and Cellular Endocrinology, 339 (1-2). pp. 34-44. ISSN 0303-7207

Chika , A., Gard, P.R., Ingram, M.J. and Moss, G.P. (2010) Synthesis and ACE-inhibitory potency of captopril branched chain ester prodrugs Journal of Pharmacy and Pharmacology, 62 (10). pp. 1374-1375. ISSN 0022-3573

Golding, Bruno J. D., Overall, A.D.J., Brown, Graham and Gard, P.R. (2010) Strain differences in the effects of Angiotensin IV on mouse cognition European Journal of Pharmacology, 641 (2-3). pp. 154-159. ISSN 0014-2999

Whale, R., Beacher, F., Golding, B., Gard , P.R. and Critchley, H. (2010) The acute effect of tryptophan depletion on serum neurotrophin levels (BDNF, FGF2, and S100B) in healthy subjects Psychopharmacology, 213 (2-3). pp. 651-652. ISSN 0033-3158

GARD, PAUL (2010) Implications of the angiotensin converting enzyme gene insertion/deletion polymorphism in health and disease: a snapshot review International Journal of Molecular Epidemiology and Genetics, IJMEG, 1 (2). pp. 145-147. ISSN 1948-1756

Gard, P.R. (2010) Non-adherence to antihypertensive medication and impaired cognition: which comes first? International Journal of Pharmacy Practice , 18 (5). pp. 252-259. ISSN 0961-7671

Cohen, J., Gard, P.R., Haq, I. and Llewelyn, M. (2009) An academia-industry partnership The Lancet, 374 (9693). p. 880. ISSN 0140-6736

Gullick, D.R., Ingram, M.J., Pugh, W.J., Cox, P.A., Gard, P.R. and Smart, J.D. (2009) Metabolism of captopril carboxyl ester derivatives for percutaneous absorption Journal of Pharmacy & Pharmacology, 61 (2). pp. 159-165. ISSN 0022-3573

Sosabowski, M.H. and Gard, P.R. (2008) Pharmacy education in the United Kingdom American Journal of Pharmaceutical Education, 72 (6). ISSN 1553-6467

Gard, P.R. (2008) Cognitive-enhancing effects of angiotensin IV BMC Neuroscience, 9 (S2). S15. ISSN 1471-2202

Golding, B., Overall, A.D.J. and Gard, P.R. (2008) The role of IRAP in the effect of angiotensin IV on cognition in the mouse Wiley-Blackwell, UK.

Samai, M., Hague, T.A., Naughton, Declan, Gard, P.R. and Chatterjee, P.K. (2008) Reduction of a paraquat-induced renal cytotoxicity by manganese and copper complexes of EGTA and EHPG Free Radical Biology and Medicine, 44 (4). pp. 711-721. ISSN 0891-5849

Samai, M, Sharpe, M.A, Gard, P.R and Chatterjee, P.K (2007) Comparison of the effects of the superoxide dismutase mimetics EUK-134 and tempol on paraquat-induced nephrotoxicity Free Radical Biology and Medicine, 43 (4). pp. 528-534. ISSN 0891-5849

Saab, Y.B, Gard, P.R and Overall, A.D.J (2007) The geographic distribution of the ACE II genotype: a novel finding Genetics Research, 89 (4). pp. 259-267. ISSN 0016-6723

Saab, Y, Gard, P.R, Yeoman, M.S, El-Moalem, H, Mfarrej, B and Ingram, M.J (2007) Renin- angiotensin- system gene polymorphisms and depression Progress in Neuro-Psychopharmacology and Biological Psychiatry, 31 (5). pp. 1113-1118. ISSN 0278-5846

Patel, B.A., Arundell, M., ALLEN, MARCUS, GARD, PAUL, O'Hare, D., Parker, K. and YEOMAN, MARK (2006) Changes in the properties of the modulatory cerebral giant cells contribute to aging in the feeding system of Lymnaea Neurobiology of Aging, 27 (12). pp. 1892-1901. ISSN 0197-4580

Arundell, M, Patel, B.A, Straub, V, Allen, M.C., Janse, C, O'Hare, D, Parker, K, Gard, P.R and Yeoman, M.S (2006) Effects of age on feeding behavior and chemosensory processing in the pond snail, Lymnaea stagnalis Neurbiology og Aging, 27 (12). pp. 1880-1891. ISSN 0197-4580

Taghizadeh, A.K., El Madani, A., GARD, PAUL, Li, C.-Y., Thomas, P.J. and Denyer, S.P. (2006) When does it hurt? Pain during flexible cystoscopy in men Urologia Internationalis, 76 (4). pp. 301-303. ISSN 0042-1138

Patel, B.A., Arundell, M., Allen, M.C., Gard, P.R, Parker, K. and Yeoman, M.S. (2006) Changes in the properties of the modulatory cerebral giant cells contribute to aging in the feeding system of Lymnaea Neurobiology of Aging, 27 (12). pp. 1892-1901.

Gard, P.R. (2005) The brain renin-angiotensin system: a target for novel antidepressants and anxiolytics Drug development research, 65 (4). pp. 270-277. ISSN 0272-4391

Gard, P.R (2004) Angiotensin as a target for the treatment of Alzheimer's disease, anxiety and depression Expert Opinions on Therapeutic Targets, 8 (1). pp. 7-14. ISSN 1472-8222

Gard, P.R. and Rusted, J.M. (2004) Angiotensin and Alzheimer´s disease: therapeutic prospects Expert Review of Neurotherapeutics, 4 (1). pp. 87-96.

Saab, Y.B., Mrouch, M.A. and Gard, P.R. (2004) Renin angiotensin system polymorphisms and associated diseases Pan Arab medical journal, 1 . pp. 43-48.

Lim, K.S., Khaw, P.T, Faragher, R.G.A, Gard, P.R, Olliff, C.J, Hanlon, G.W, Wong, L, Reed, S, Denyer, S.P, Allan, B, Willlis, S and Miur, A (2003) Corneal endothelial cell damage from glaucoma drainage device materials Cornea, 22 (4). pp. 352-354. ISSN 0277-3740

Pountney, TE, Mandy, A. and Gard, P.R. (2003) Repeatability and limits of agreement in measurement of hip migration percentage in children with bilateral cerebral palsy Physiotherapy, 89 (5). pp. 276-281. ISSN 0031-9406

Braszko, J.J., Karwowska-Polecka, W., Halicka, D. and Gard, P.R. (2003) Captopril and Enalapril improve cognition and depressed mood in hypertensive patients Basic and Clinical Physiology and Pharmacology, 14 (4). pp. 323-343. ISSN 0334-1534

Pountney, TE, Mandy, A., Green, E. and Gard, P.R. (2002) Management of hip dislocation with postural management Child: care, health and development, 28 (2). pp. 179-185. ISSN 1365-2214

Gard, P.R. (2002) The role of angiotensin II in cognition and behaviour European journal of pharmacology, 438 (1-2). pp. 1-14. ISSN 0014-2999

Lim, K.S., Allan, B., Khaw, P.T., Willis, S., Lloyd, A.W., Muir, A., Gard, P.R., Faragher, R.G.A., Olliff, C.J., Hanlon, G.W., Wong, L., Reed, S. and Denyer, S.P. (2001) Experimental flow studies in glaucoma drainage device development British journal of ophthalmology, 85 (10). pp. 1231-1236. ISSN 0007-1161

Gard, P.R., Haigh, S.J., Cambursano, P.T. and Warrington, C.A. (2001) Strain differences in the anxiolytic effects of losartan in the mouse Pharmacology biochemistry and behavior, 69 (1-2). pp. 35-40. ISSN 0091-3057

This list was generated on Tue Jun 11 16:16:25 2013 BST.