Dr Liz James
Principal Lecturer
contact:
Pharmacy and Biomolecular Sciences
Moulsecoomb
Brighton
BN2 4GJ
Telephone: +44 (0)1273 642038
+44 (0)1273 641032
Email: S.E.James@brighton.ac.uk
Research Interests
- Wound healing and tissue reconstruction
- Novel wound dressings
- Biomaterial scaffolds
- Cell interactions with scaffolds - skin, eyes & bone
- Clinical translation of research
- Skin epithelium-replacement in burn patients
- Corneal epithelium-reconstruction of damaged corneas
- Buccal epithelium-soft tissue reconstruction
- Mammalian primary cell culture
Research Publications
Hill, R.P., Gledhill, K., Gardner, A., Higgins, C.A., Crawford, H., Lawrence, C., Hutchison, C.J., Owens, W.A., Kara, B., JAMES, S.Elizabeth and Jahoda, C.A. (2012) Generation and characterization of multipotent stem cells from established dermal cultures PLoS ONE, 7 (11). ISSN 1932-6203
SHEVCHENKO, ROSTISLAV, Sibbons, P.D., Sharpe, J.R. and JAMES, S.Elizabeth (2011) A novel skin substitute biomaterial to treat full-thickness wounds in a burns emergency care In: Mikhalovsky, S. and Khajibaev, A., eds. Biodefence: advanced materials and methods for health protection. NATO Science for Peace and Security Series A: Chemistry and Biology . Springer, Netherlands. ISBN 9789400702165
SHEVCHENKO, ROSTISLAV, Eeman, M., SAVINA, IRINA, ALLAN, IAIN, JAMES, STUART, Salmon, M., MIKHALOVSKY, SERGEY and JAMES, S.Elizabeth (2010) A step towards an artificial skin: a novel supermacroporous anisotropic cryogel for wound healing applications International Journal of Artificial Organs, 33 (7). ISSN 0391-3988
SHEVCHENKO, ROSTISLAV, JAMES, STUART and JAMES, S.Elizabeth (2010) A review of tissue-engineered skin bioconstructs available for skin reconstruction Interface, 7 (43). ISSN 1742-5662
Hallam, M.J., Allen, J.M., JAMES, S.Elizabeth, Donaldson, P.M.W., Davies, J.G., HANLON, GEOFF and Dheansa, B. (2010) Potential sub-theraputic linezolid and meropenem antibiotic concentrations in a patient with severe burns and sepsis Journal of Burn Care and Research, 31 (1). pp. 207-209. ISSN 1559-047X
JAMES, S.Elizabeth, Booth, S., Dheansa, B., Man, D.J., Reid, M.J., SHEVCHENKO, ROSTISLAV and Gilbert, P. (2010) Sprayed cultured autologous keratinocytes used alone or in combination with meshed autografts to accelerate wound closure in difficult-to-heal burns patients Burns, 36 (3). pp. 10-20. ISSN 0305-4179
ALLAN, IAIN, SHEVCHENKO, ROSTISLAV, Rowshanravan, B., Karabanova, B.L.V., Jahoda, C.A. and JAMES, S.Elizabeth (2009) The use of confocal laser scanning microscopy to assess the potential suitability of 3-D scaffolds for tissue regeneration, by monitoring extra-cellular matrix deposition and by quantifying cellular infiltration and proliferation Soft Materials, 7 (4). pp. 1-23. ISSN 1539-445X
JAMES, S.Elizabeth, Booth, S., Gilbert, P., Jones, I. and SHEVCHENKO, ROSTISLAV (2009) Clinical approaches to skin regeneration In: Santin, Matteo, ed. Strategies in regenerative medicine: integrating biology with materials design. Springer, London, UK. ISBN 9780387746593
SHEVCHENKO, ROSTISLAV, Sharpe, J.R., Sibbons, P.D. and JAMES, S.Elizabeth (2008) Preclinical assessment of the collagen-based paste Permacol(tm) for the role of a dermal substitution in full-thickness wounds Kharkiv Surgical School, 2 (29). pp. 308-319.
SHEVCHENKO, ROSTISLAV, Sibbons, P.D., Sharpe, J.R. and JAMES, S.Elizabeth (2008) Use of a novel porcine collagen paste as a dermal substitute in full-thickness wounds Wound Repair and Regeneration, 16 (2). pp. 198-207. ISSN 1067-1927
Reid, M.J., Currie, L.J., JAMES, S.Elizabeth and Sharpe, J.R. (2007) Effect of artificial dermal substitute, cultured keratinocytes and split thickness skin graft on wound contraction Wound Repair and Regeneration, 15 (6). ISSN 1067-1927
Reid, M.J., Currie, L.J., JAMES, S.Elizabeth and Sharpe, J.R. (2007) Effect of artificial dermal substitute, cultured keratinocytes and split thickness skin graft on wound contraction Wound Repair and Regeneration, 15 (6). ISSN 1067-1927
Sharpe, J.R., Daya, S., Dimitriadi, M., Martin, R. and JAMES, S.Elizabeth (2007) Survival of cultured allogeneic limbal epithelial cells following corneal repair Tissue Engineering, 13 (1). pp. 123-132. ISSN 1076-3279
JAMES, S.Elizabeth, ILLSLEY, MATTHEW, JAMES, STUART, Mendoza, E., Silva, S.R.P., Vadgama, P., Tomlins, Paul and MIKHALOVSKY, SERGEY (2006) The interaction of nanostructured biomaterials with human cell cultures. The choice of cell cultures for use as biocompatability probes In: Blitz, J.P. and Gun'ko, V.M., eds. Surface chemistry in biomedical and environmental science. Springer, Netherlands. ISBN 9781402047398
Daya, S., Watson, A., Sharpe, J.R., Giledi, O., Rowe, A., Martin, R. and JAMES, S.Elizabeth (2005) Outcomes and DNA analysis of ex vivo expanded stem cell allograft for ocular surface reconstruction Ophthalmology, 112 (3). pp. 470-477. ISSN 0161-6420
Pavey, K.D., JAMES, STUART, JAMES, S.Elizabeth, MIKHALOVSKA, LYUBA, Tomlins, Paul, Paul, F. and MIKHALOVSKY, SERGEY (2003) Real-time monitoring of cellular integration within bulk soft tissue scaffold materials Journal of Materials Chemistry, 13 (4). pp. 654-656. ISSN 0959-9428
Currie, L.J., Martin, R., Sharpe, J.R. and JAMES, S.Elizabeth (2003) A comparison of keratinocyte cell sprays with and without fibrin glue Burns, 29 (7). pp. 677-685. ISSN 0305-4179
Jones, I., JAMES, S.Elizabeth, Rubin, P. and Martin, R. (2003) Upward migration of cultured autologous keratinocytes in Integra (TM) artificial skin: a preliminary report Wound Repair and Regeneration, 11 (2). pp. 132-138. ISSN 1067-1927
JAMES, S.Elizabeth (2002) Cultured keratinocytes: experimental and clinical directions in the quest for tissue engineering new skin In: Munster, A.M., Achauer, B.M. and Horch, R.E., eds. Cultured human keratinocytes and tissue engineered skin substitutes. Thieme, Stuttgart; New York. ISBN 9783131301611
JAMES, S.Elizabeth, Rowe, A., Ilari, L., Daya, S. and Martin, R. (2001) The potential for eye bank limbal rings to generate cultured corneal epithelial allografts Cornea, 20 (5). pp. 488-494. ISSN 0277-3740
JAMES, S.Elizabeth, FARAGHER, RICHARD, Burke, J.F., Shall, S. and Mayne, L.V. (2000) Werner's syndrome T lymphocytes display a normal in vitro life-span Mechanisms Of Ageing And Development, 121 (1-3). ISSN 0047-6374
Cole, J., Arlett, C.F., Green, M.H.L., JAMES, S.Elizabeth, Henderson, L., Cole, H., Sala-Trepat, M., Benzi, R., Price, M.L. and Bridges, B.A. (1989) Measurement of mutant frequency to 6-thioguanine resistance in circulating T-lymphocytes for human population monitoring In: Jolles, G. and Cordier, A., eds. New trends in genetic risk assessment. Academic Press, London. ISBN 0123881765
Cole, J., Arlett, C.F., Green, M.H.L., Harcourt, S.A., Priestley, A., Henderson, L., Cole, H., JAMES, S.Elizabeth and Richmond, F. (1988) Comparative human cellular radiosensitivity: II. The survival following gamma-irradiation of unstimulated (G0) T-lymphocytes, T-lymphocyte lines, lymphoblastoid cell lines and fibroblasts from normal donors, from ataxia-telangiectasia patients and from ataxia-telangiectasia heterozygotes International Journal Of Radiation Biology, 54 (6). ISSN 0955-3002
Cole, J., Green, M.H.L., JAMES, S.Elizabeth, Henderson, L. and Cole, H. (1988) A further assessment of factors influencing measurements of thioguanine-resistant mutant frequency in circulating T-lymphocytes Mutation Research - Genetic Toxicology, 204 (3). ISSN 0165-1218
Henderson, L., Cole, H., Cole, J., JAMES, S.Elizabeth and Green, M.H.L. (1986) Detection of somatic mutations in man: evaluation of the microtitre cloning assay for T-lymphocytes Mutagenesis, 1 (3). ISSN 0267-8357
Henderson, L., Cole, H., Arlett, C.F., JAMES, S.Elizabeth, Cole, J., Lehmann, A., Rosenbloom, L., Redmond, T. and Meller, S. (1985) Diagnosis of ataxia-telangiectasia by T-lymphocyte cloning assay Lancet, 2 (8466). ISSN 0140-6736
JAMES, S.Elizabeth, Arlett, C.F., Green, M.H.L. and Bridges, B.A. (1983) Radiosensitivity of human T-lymphocytes proliferating in long term culture International Journal Of Radiation Biology, 44 (5). ISSN 0955-3002
JAMES, S.Elizabeth, Dean, C.J. and Alexander, P. (1980) Failure to detect autologous antibodies in the remission sera of patients with AML: complications introduced by the presence of rheumatoid factor British Journal of Cancer, 42 (3). ISSN 0007-0920


