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Drug Delivery and Chemiembolotherapy

The Biomedical Materials group have developed significant expertise and experience of developing drug delivery vehicles for controlled delivery.

The group have developed a close working relationship with Biocompatibles UK Ltd developing and characterising polymer-based beads for use in chemiembolotherapy for solid tumours.

Confocal microscopy images of polymer-based drug delivery vehicles

Confocal microscopy images of polymer-based drug delivery vehicles for the treatment of sold tumours.

Recent Publications

J P. Salvage, S F. Rose, G J. Phillips, G W. Hanlon, A W. Lloyd, I Y. Ma, S P. Armes, N C. Billingham, A L. Lewis (2005) Novel biocompatible phosphorylcholine-based self-assembled nanoparticles for drug delivery, Journal of Controlled Release 104 (2): 259-270

A L. Lewis, M. V Gonzales, S W. Leppard, J Brown, P W. Stratford, G. J. Phillips, A. W. Lloyd. (2007) Doxorubicin Eluting Beads - 1:Effects of Drug Loading on Bead Characteristics and Drug Distribution, J Mater Sci: Mater Med., 18 (9); 1691-1699

M. V. Gonzales, Y. Tang, G. J. Phillips, A. W. Lloyd, B. Hall, P.W. Stratford & A.W. Lewis (2007) Doxorubicin Eluting Beads – 2: Methods for Evaluating Drug Elution and In-vitro:In-vivo Correlation, J Mater Sci: Mater Med. (In Press)

Confocal microscopy images of polymer-based drug delivery vehicles