Projects per year
Organisation profile
Profile Information
Advances in our understanding of pathology and pharmacology have led to an explosion of new medicines in the past 30 years. Large, biological molecules are now commonplace in the formularies of clinical specialities, and smaller drug compounds which act on a diverse range of targets are providing clinicians and patients with much needed options.
Yet despite this, medicines, which are the most common therapeutic intervention, carry a risk of harm, and in some patient groups are a significant cause of iatrogenic injury. There is also a paucity of evidence regarding using medicines simultaneously in patients with multi-morbidity (e.g. the elderly, or new-born infants) as they are not consistently included in clinical trials. Where data is available, it is interesting to note that there is considerable variation in the therapeutic response patients show to medicines – only some of which we are beginning to understand. Together, these factors make prescribing complex, and prone to error.
The medicines optimisation research group therefore has three clear goals to improve our understanding of how use medicines safely and effectively:
The science of medicines: Develop world-class research that utilises basic science research expertise and techniques to increase our understanding of medicines. Areas of research expertise include: pharmacokinetics, pharmacology and microbiology; pharmaceutical formulation; clinical bioanalysis; pharmacogenetics and pharmacogenomics.
The clinical use of medicines: Develop world-class research that examines human behaviours and psychology in health and disease. Areas of research expertise include: behavioural medicine, health psychology, and paediatrics.
Medicines related education, training and support: Identify and test new approaches to educate and assess the current and future workforce with regards to medicines optimisation, and medicines optimisation research.
Our external partners include, Brighton and Sussex University Hospitals NHS Trust and Brighton and Sussex Medical School
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Collaborations and top research areas from the last five years
Profiles
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Safoora Azimi-Yancheshmeh
Person: Academic
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Integrating Antiracism, Social Justice and Equity into the Chemical Sciences Curriculum
30/10/23 → 30/04/26
Project: Charities
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Understanding the heterogeneity of diseased tissue using state of the art omics technology for the prevention and treatment of disease
Yeoman, M., Patel, B., Flint, M., Staines, K., Faragher, R., Dymond, M., Stewart, N., Santin, M., Shakur, R., Mullen, L., Waddell, S. & Hafezparast, M.
1/10/23 → 31/03/26
Project: Research Councils / Government Depts.
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A biomimetic macromolecular platform for tissue healing and diagnostics at medical device interfaces: a personalised wound dressing model
Santin, M., Georgoulas, A., Harris, P., Crua, C., Sarker, D., Elsom, J., Sandeman, S., Forss, R., Redhead, L., Terrazzini, N., Saberianpour, S., Melotto, G., Hesketh, A. & Sinha, A.
1/06/22 → 31/03/28
Project: Research Councils / Government Depts.
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Evaluating diverse electrode surface patterns of 3D printed carbon thermoplastic electrochemical sensors
Miller, C., Keattch, O., Shergill, R. & Patel, B., 19 Jan 2024, In: The Analyst. 149, 5, p. 1502-1508 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Pristine Ti3C2Tx MXene Enables Flexible and Transparent Electrochemical Sensors
Noriega Pedraza, N., Shekhirev, M., Shuck, C., Salvage, J., VahidMohammadi, A., Dymond, M., Lacey, J., Sandeman, S., Gogotsi, Y. & Patel, B., 23 Jan 2024, In: ACS Applied Materials and Interfaces. 16, 5, p. 6569-6578 10 p.Research output: Contribution to journal › Article › peer-review
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Sickle cell disease: causes, treatments and the patient experience
Spurway, A., George, S., Thompson, C., Weeks, S. & Teo, X. Y., 9 Jan 2024, In: The Pharmaceutical Journal.Research output: Contribution to journal › Article › peer-review
Activities
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NHSBT Community Grants Programme Stakeholder Meeting
Simonne Weeks (Presenter), Gunnika Jain (Presenter) & Lois Leese (Presenter)
11 Sept 2023Activity: External talk or presentation › Invited talk
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FIP Webinar on Sports pharmacy practice and education
Claire May (Presenter)
1 Aug 2023Activity: External talk or presentation › Oral presentation
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FIP Webinar:Sports Pharmacy Practice and Education: A global overview
Claire May (Participant)
8 Dec 2022Activity: Events › Outreach and Public Engagement