Output
Maher J., Hunter A.C., Mabley J.G., Lippiat J., and Allen M.C. Smooth muscle relaxation and activation of the large conductance Ca (++)-activated K(+) (BKCa) channel by novel oestrogens. Br J Pharmacol 169(5): 1153-65, 2013
Mabley J.G., Gordon S., and Pacher P., Nicotine exerts an anti-inflammatory effect in a murine model of acute lung injury. Inflammation 34(4):231-7, 2011
Katsoulieris E., Mabley J.G., Samai M., Sharpe, M.A., Green I.C., and Chatterjee P.K., Lipotoxicity in renal proximal tubular cells: relationship between endoplasmic reticulum stress and oxidative stress pathways. Free Radic Biol Med 48(12): 1654-62, 2010.
Mabley J.G., Pacher P. and Szabo C., Activation of the cholinergic anti-inflammatory pathway reduces ricin-induced mortality and organ failure in mice. Mol Med 15(5-6): 166-72, 2009.
Mabley J.G., Pacher P., Murthy K.G., Williams W., Southan G.J., Salzman A.L., and Szabo C., The novel inosine analogue, INO-2002, exerts an anti-inflammatory effect in a murine model of acute lung injury. Shock, 32(3):258-62 2009.
Helyar S.G., Patel B., Headington K., El Assal M., Chatterjee P.K., Pacher P. and Mabley J.G., PCB-induced endothelial cell dysfunction: Role of poly(ADP-ribose) polymerase. Biochem Pharmacol, 78(8):959-65 2009.
Katsoulieris E., Mabley J.G., Samai M., Green I.C., and Chatterjee P.K., alpha-Linolenic acid protects renal cells against palmitic acid lipotoxicity via inhibition of endoplasmic reticulum stress. Eur J Pharmacol 623(1-3): 107-12, 2009.
Rajesh M., Mukhopadhyay P., Batkai S., Mukhopadhyay B., Patel V., Hasko G., Szabo C., Mabley J.G., Liaudet L., and Pacher P, Xanthine oxidase inhibitor allopurinol attenuates the development of diabetic cardiomyopathy. J Cell Mol Med 13 (8B): 2330-41, 2009.
Mabley, J., Pacher, P., Murphy, K., Williams W., Southan G., Salzman A. and Szabo, C. The novel inosine analogue, INO-2002, protects against diabetes development in multiple-low-dose-streptazotocin and NOD mouse models of Type I diabetes. J. Endocrinol, 198:581-89, 2008.
Mabley, J.G. and Szabo, C. Inflammatory disease and sunlight: the vitamin D-poly (ADP-ribose) polymerase connection. Future Rheumatol 3(2):169-81, 2008.
Kevin Butler, Jenny Rusted, Paul Gard, Anne Jackson(2013) Performance monitoring in current and former smokers. Biennial Meeting of the European Behavioural Pharmacology Society, La Rochelle, France. Sept 2013.
Austin AJ, Duka T, Rusted J, Jackson A (2012) Effects of varenicline on aspects of inhibitory control in smokers 14th Annual European Meeting of the Society for Research on Nicotine and Tobacco (SRNT-E) Helsinki, Finland. Aug-Sept 2012.
Nesic, J., Duka, T., Rusted, J.M. and Jackson, A. (2011) A role for glutamate in subjective response to smoking and its action on inhibitory control. Psychopharmacology, 216 . pp. 29-42. ISSN 0033-3158.
Nesic, J., Rusted, J., Duka, T. and Jackson, A. (2011) Degree of dependence influences the effect of smoking on cognitive flexibility. Pharmacology Biochemistry and Behaviour, 98 (3). pp. 376-384. ISSN 0091-3057.
Anne Jackson (2010) Cognitive Enhancers: Role of the Glutamate System. Encyclopedia of Psychopharmacology, Part 3, pp 317-322 Ed: IP Stolerman. Springer
1Jackson, A., Nesic, J., Groombridge, C., Clowry, O., Rusted, J. and Duka, T. (2009) Differential involvement of glutamatergic mechanisms in the cognitive and subjective effects of smoking. Neuropsychopharmacology, 34 (2). pp. 257-265. ISSN 1470-634X.
Ayoub, M., Lethem, M. I., Lansley, A. B. (2013 Excipients used in intranasal formulations: do they affect mucociliary function? Presented at the Annual meeting of the Academy of Pharmaceutical Sciences, Edinburgh
Lee D. F., Lethem, M. I., Lansley, A. B. (2013) The use of in vitro models to study drug permeability in the presence of mucus. Presented at the Annual meeting of the Academy of Pharmaceutical Sciences, Edinburgh
Martin G. P. and Lansley A. B. (2013) Intranasal Drug Delivery in Aulton’s Pharmaceutics. The Design and Manufacture of Medicines. Eds. Aulton, M.E. and Taylor, K. Churchill Livingstone Elsevier, London
Lee D. F., Lethem, M. I., Lansley, A. B. (2012) Evaluation of Calu-3 cells as an in vitro model to investigate drug permeability in the presence of mucus. Presented at the Annual meeting of the British Association for Lung Research, Southampton
Field, J., Lethem, M. I., Lansley, A. B. (2011) Endothelin increases ciliary beat frequency of ovine airway epithelium via its interaction with ETA receptors. Pulmonary Pharmacology and Therapeutics. 24(5):602-9.
Cranage, M., Fraser, C., Stevens, Z., Huting, J., Chang, M., Jeffs, S., Seaman, M., Cope, E., Cole, T. & Shattock, R. 2010.
Repeat vaginal immunization with oligomeric HIV-1 clade C gp140 in the absence of adjuvant induces serum and mucosal antibody responses.
Mucosal Immunology 3, 57-68
Corti, D., Langedijk, J.P.M., Hinz, A., Seaman, M.S., Vanzetta, F., Fernandez-Rodriguez, B.M., Silacci, C., Pinna, D., Jarrossay, D., Balla-Jhagjhoorsing, S., Willems, B., Zekveld, M.J., Dreja, H., O’Sullivan, E., Pade, C., Orkin, C., Jeffs, S.A., Montefiori, D.C., Davis, D., Weissenhorn, W., McKnight, A., Heeney, J.L., Sallusto, F., Sattentau, Q., Weiss, R.A. & Lanzavecchia, A. 2010.
Analysis of Memory B-cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1 infected individuals.
PLoS ONE 5(1) e8805
Kong, L., Sheppard, N.C., Stewart-Jones, G., Robson, C.L., Chen, H., Xu, X., Krashias, G., Bonomelli, C., Scanlan,C.N., Kwong, P.D., Jeffs, S.A., Jones, I.M. & Sattentau, Q.J. 2010. Expression system-dependent modulation of HIV-1 envelope glycoprotein antigenicity and immunogenicity.
Journal of Molecular Biology 403, 131-147
Wegmann, F., Krashias, G., Lühn, K., Laamanen, K., Jeffs, S.A., Vieira, S., Shattock, R.J. & Sattentau, Q.J. 2010.
A novel strategy for inducing enhanced mucosal HIV-1 antibody responses in an anti-inflammatory environment
PLoS ONE (6) e15861
Hijazi, K., Wang, Y., Jeffs, S.A., Longstaff, C., Stieh, D., Haggarty, B., Vanham, G., Schols, D., Balzarini, J., Hoxie, J., Shattock, R. & Kelly, C. 2011
DC-SIGN increases the affinity of HIV-1 envelope glycoprotein interaction with CD4
PLoS ONE 6 (12) e28307
Lewis, D.J., Fraser, C.A., Mahmoud, A.,Wiggins, R.C., Woodrow, M., Cope, A., Cai, C., Giemza, R., Jeffs, S.A., Abdul Hussein, S., Durham, N.D., Manoussaka, M., Cole, T., Cranage, M.P., Shattock, R.J. & Lacey, C.J. 2011
Phase I clinical trial of an HIV-1CN54, clade C, trimeric envelope vaccine candidate delivered vaginally
PLoS ONE 6(9) e25165
Neuberger, M., Pruzina, S., Williams, G., Kaneva, G., Davies, S., Martín-López, A., Bruggemann, M., Vieira, S., Jeffs, S.,& Sattentau, Q. 2011
Human monoclonal antibodies to HIV-1 gp140 from mice bearing
YAC-based human immunoglobulin transloci
Protein Engineering Design and Selection 24, 791-799
Tang, J., Wang, L., Markiv, A., Jeffs, S.A., Dreja, H., McKnight, A., He, M. & Kang, A.S. 2012
Rapid Identification of Human Anti-HIV-1 Antibodies from Patient Libraries by Eukaryotic Ribosome Display
Human Antibodies 21, 1-11
Richardson SJ, Willcox A, Bone AJ, Foulis AK, Morgan NG. The prevalence of enteroviral capsid protein vp1 immunostaining in pancreatic islets in human type 1 diabetes. Diabetologia 2009; 52: 1143-115.
Aldibbiat A, Marriott C, Scougall K, Campbell S, Huang G, Macfarlane W M, Shaw J. (2009) Inability to process and store proinsulin in transdifferentiated pancreatic acinar cells lacking the regulated secretory pathway. J Endocrinol. 199(1):149.
Willcox A, Richardson SJ, Bone AJ, Foulis AK, Morgan NG. Analysis of islet inflammation in human type 1 diabetes. Clin Exp Immunol 2009: 155: 173-181
Willcox A, Richardson SJ, Bone AJ, Foulis AK, Morgan NG. Evidence of increased islet cell proliferation in patients with recent onset type 1 diabetes. Diabetologia 2010: 53: 2020 – 2028
Willcox A, Richardson SJ, Bone AJ, Foulis AK, Morgan NG. Immunohistochemical analysis of the relationship between islet cell proliferation and the production of the enteroviral capsid protein, vp1, in the islets of patients with recent-onset type 1 diabetes. Diabetologia 2011: Short Communication; 54: 2417 – 2420
Ferris, W.F., Marriott, C.E., Ali, T., Landy, C., Campbell, S.C and Macfarlane W.M. (2011). The tumour suppressor Pdcd4 is a major transcript that is upregulated during in vivo pancreatic islet neogenesis and is expressed in both beta and ductal cell lines. Pancreas. 40(1):61-6.
Cancer
Smith AL, Sun M, Bhargava R, Stewart NA, Flint MS, Bigbee WL, Krivak TC, Strange MA, Cooper KL, Zorn KC (2013). Proteomic analysis of matched formalin-fixed, paraffin-embedded specimens in patients with advanced serous ovarian carcinoma. Proteomes 1, 240-253.
Flint MS, Baum A, Episcopo B, Knickelbein KZ, Liegey Dougall AJ, Chambers WH, Jenkins FJ (2013). Chronic exposure to stress hormones promotes transformation and tumorigenicity of 3T3 mouse fibroblasts. Stress 16:114-121.
Flint MS, Bovbjerg DH (2012). DNA damage as a result of psychological stress: implications for breast cancer. Breast Cancer Res. 14(5): 320-322. * Highly Accessed Article
Maxwell GL, Hood BL, Day R, Chandran U, Kirchner D, Bateman NW, Allard J, Miller C, Sun M, Flint MS, Kolli VS, Zahn C, Oliver J, Banerjee S, Litzi T, Parwani A, Sandburg G, Rose S, Becich M, Berchuck A, Kohn E, Risinger JI and Conrads TP (2011). Proteomic Analysis of Stage I Endometrial Cancer Tissue: Identification of Proteins Associated with Oxidative Processes and Inflammation. Gynecologic Oncology. 1;121(3):586-94.
Flint MS, Budiu RA, Teng P, Sun M, Stolz D, Lang M, Vlad AM, Hood BL and Conrads TP (2011). Restraint stress and stress hormones significantly impact T lymphocyte migration and function through specific alterations of the acting cytoskeleton. Brain behaviour & Immunity. 25(6):1187-96.
Flint MS, McCarty K, Jenkins F, Conrads TP, Sun M and Baum A (2010). Psychological stress accelerates the onset of tumour formation and alters the type and location of tumours in a DMBA mouse carcinogenesis model. Stress and Health, 27: n/a. doi: 10.1002/smi.1343
Hood BK, Grahovac J, Flint MS, Sun M, Charro N, Becker D, Wells A and Conrads TP (2010). Proteomic Analysis of Laser Capture Microdissected Melanoma Cells from Skin Organ Cultures. Journal of Proteome Research 9 (7) 3656-63.
Teng PN, Rungruang B, Hood BL, Sun M, Flint MS, Bateman NW, Dhir R, Bhargava R, Richard SD, Edwards RP, Conrads T (2010). Assessment of Buffer Systems for Harvesting Proteins from Tissue Interstitial Fluid for Proteomic Analysis. Journal of Proteome Research. 9 (8):4161-9.
Bateman NW, Sun M, Hood BL, Flint MS, Conrads TP (2010). Defining central themes in breast cancer biology by differential proteomics: conserved regulation of cell spreading and focal adhesion kinase. Journal of Proteome Research 9 (10) 5311-24.
Flint MS, Hood BL, Sun, M, Stewart NA, Jones-Laughner J, Conrads TP (2010). A Proteomic Analysis of the Murine Liver in Response to a Combined Exposure to Psychological Stress and 7,12-dimethylbenz(a)anthracene. Journal of Proteome Research 9 (1): 509-20.
Flint MS, Bateman NE, Kim G, Hood BL, Stewart NA, Conrads TP (2009). Stress hormones mediate drug resistance to paclitaxel in human breast cancer cells through a Cdk-1 dependent pathway.Psychoneuroendocrinology 34 (10):1533-41.
Knickelbein KZ, Flint MS, Jenkins F, Baum A (2008). Psychological stress and oxidative damage in lymphocytes of aerobically fit and unfit individuals Journal of Applied Biobehavioral Research 13 (1): 1-19.