• Skip to content
  • Skip to footer
  • Accessibility options
University of Brighton
  • About us
  • Business and
    employers
  • Alumni and
    supporters
  • For
    students
  • For
    staff
  • Accessibility
    options
Open menu
Home
Home
  • Close
  • Study here
    • Meet us
    • Open days
    • Virtual tours
    • Upcoming events
    • Applicant days
    • Meet us in your country
    • Chat to our students
    • Ask us a question
    • Order a prospectus
    • Our campuses
    • Our four campuses
    • Accommodation options
    • Our halls
    • Helping you find a home
    • What you can study
    • Find a course
    • Full A-Z course list
    • Explore our subjects
    • Our academic departments
    • How to study with us
    • Undergraduate application process
    • Postgraduate application process
    • International student application process
    • Apprenticeships
    • Applying through Clearing
    • Transfer from another university
    • Fees and financial support
    • Undergraduate finance
    • Postgraduate finance
    • Our funding and support options
    • Supporting you
    • Your wellbeing
    • Student support and guidance tutors
    • Study skills support
    • Careers and employability
  • Research
    • Research and knowledge exchange
    • Research and knowledge exchange organisation
    • The Global Challenges
    • Centres of Research Excellence (COREs)
    • Research Excellence Groups (REGs)
    • Our research database
    • Information for business
    • Community University Partnership Programme (CUPP)
    • Postgraduate research degrees
    • PhD research disciplines and programmes
    • PhD funding opportunities and studentships
    • How to apply for your PhD
    • Research environment
    • Investing in research careers
    • Strategic plan
    • Research concordat
    • News, events, publications and films
    • Featured research and knowledge exchange projects
    • Research and knowledge exchange news
    • Inaugural lectures
    • Research and knowledge exchange publications and films
    • Academic staff search
  • About us
  • Business and employers
  • Alumni, supporters and giving
  • Current students
  • Staff
  • Accessibility
Search our site
Book on beach
Research and knowledge exchange
  • Postgraduate research degrees
  • Research features
  • Research organisation
  • Research environment
  • Postgraduate research degrees
    • Postgraduate research degrees
    • PhD-films
    • Our postgraduate research disciplines
    • Research Masters
    • Funding and studentships
    • Support and training
    • Postgraduate open evening
    • Apply for a PhD
    • Contact us
  • Research students
    • Research students
    • Alex Fitch
    • Alexander Kolliari-Turner
    • Arben Lubach
    • Ash Willmott
    • Bahar Khayamian Esfahani
    • Caroline Hamilton
    • Catherine Payne
    • Charlotte Coombs
    • Claudia Treacher
    • Conor Sheehan
    • Conor Strong
    • Daniel Nsikane
    • David Felix
    • Dicle Kortantamer
    • Emelia Akashah Patah Akhir
    • Filippo Gerbino
    • Gelu Varghese
    • Gregor Eichhorn
    • Hannah Ray
    • Hanno Martens
    • Hiba Almasri
    • Indra Kusumawardhana
    • Isa Kwabe
    • Jane Frances Dunlop
    • Jennifer Holland
    • Jocelyn Bailey
    • Josie Maitland
    • Julian D Riano
    • Katie McCallum
    • Kimberley Chandler
    • Lilián Sánchez-Moreno
    • Lujain Yousif Mirza
    • Majed Al-Jefri
    • Mana Al Mashreef
    • Maria Gebbels
    • Mariana Lima
    • Marta Falcinelli
    • Mary Edward
    • Matyas Varga
    • Merryn Haines-Gadd
    • Mohammed Ghazi Al-Obeidallah
    • Myrsini Samaroudi
    • Nagham Al-Qaysi
    • Niall Walkden
    • Oliver Gibson
    • Samuel Penny
    • Shafq Al-Azzawi
    • Shai Kassirer
    • Tom Raven
    • Wulan Koagouw
    • Yahya Ibraheem
    • Aaron Greenhouse-Tucknott
    • Antonia Karanikolou
    • Ben Duncan
    • Carl James
    • Emily Watkins
    • Gareth Turner
    • Jake Butterworth
    • James Wrightson
    • Jet Van Zalen
    • Kirsty Waldock
    • Marina Garcia Hortal
    • Rebecca Relf
    • Rosemary Twomey
  • Charlotte Coombs

Charlotte Coombs

After Charlotte completed her BSc (Hons) in Applied Sport Science at the University of Edinburgh, she went on to study for a MSc in Exercise Physiology at Loughborough University. Her MSc dissertation focused on the expression of GHS-R1a on immune cells in response to acute and regular exercise. Alongside her PhD, she is also working towards her BASES sport science physiological support accreditation.

Email address: C.V.Coombs@brighton.ac.uk

Qualification: MPhil/PhD

Timeframe: Three years

Charlotte-Coombs

Thesis title

Investigation of the effects of blood borne factors, altered by exercise, on mesenchymal stem cell characteristics

My research

Stem cells are unspecialised cells that have the ability to differentiate into specialised cells for tissue growth, repair and regeneration, and emerging research has indicated that exercise may be used as a tool to exploit their healing capabilities. Mesenchymal stem cells (MSCs) possess many properties that promote tissue repair which makes them a favourable stem cell source for treating many diseases and injuries, however little information exists about how they respond to an exercise stimulus. My PhD research is therefore investigating the effect of exercise-induced changes in blood borne factors, upon MSC characteristics. By further understanding this, the information can then be used to identify the optimal exercise for promoting the endogenous stem cell recruitment and function, and understand the principle factors involved that may lend themselves to improving in vitro culture of such cells and autologous transplant or re-infusion.

Charlotte has also received a research grant to collaborate with the Molecular Muscle Physiology Lab at the University of Illinois at Urbana-Champaign where she will continue to build upon the data obtained in her PhD studies.

Funder

University of Brighton – Scheme B Funded Studentship

Supervisors

Associate Professor Peter Watt

Anna Guildford

Professor Yannis Pitsiladis

Back to top
  • Facebook
  • Twitter
  • Instagram
  • TikTok
  • YouTube
  • LinkedIn icon

Contact us

University of Brighton
Mithras House
Lewes Road
Brighton
BN2 4AT

Main switchboard 01273 600900

Course enquiries

Sign up for updates

University contacts

Report a problem with this page

Quick links Quick links

  • Courses
  • Open days
  • Order a prospectus
  • Academic departments
  • Academic staff
  • Professional services departments
  • Jobs
  • Privacy and cookie policy
  • Accessibility statement
  • Libraries
  • Term dates
  • Maps
  • Graduation
  • Site information
  • Online shop
  • COVID-19
  • The Student Contract

Information for Information for

  • Current students
  • International students
  • Media/press
  • Careers advisers/teachers
  • Parents/carers
  • Business/employers
  • Alumni/supporters
  • Suppliers
  • Local residents