CAERvest® is a novel endothermic hypothermic device for core temperature cooling created by BodyChillz Ltd., a Gatwick-based company in Surrey. We have planned and implemented numerous studies to assess and investigate the cooling device within a range of populations and scenarios.
Active cooling treatment is used to reduce an abnormally or dangerously elevated core body temperature, as in heat related illnesses (HRI). It may also be used to reduce a patient’s core body temperature below normal with targeted temperature management [TTM] during cardiac surgery and as neuroprotective treatment to reduce brain damage following a loss of blood supply.
HRI present on a continuum of pathological states that range from mild to severe, whereby if they are undetected or ineffectively treated, mild HRI can lead to heatstroke, a severe, life-threatening illness. Exertional heatstroke (EHS), a consequence of attenuated whole-body heat loss and the inability to dissipate metabolic heat production, can occur while physically active in either temperate or, hot humid conditions. Predisposing risk factors include lack of acclimatisation, dehydration, sleep deprivation, low aerobic fitness and diverse biophysical characteristics, meaning the onset can be sporadic and unpredictable.
Core body temperature cooling is employed within sporting and occupational health settings prior to and between aerobic exercise or fire fighting tasks, which have shown to improve performance in heat stress and reduce physiological and, or perceptual strain. Methods employed to actively cool vary according to setting and application, while HRI treatment is largely dependent upon the duration and extent to which core body temperature exceeds critical levels. Examples of these modalities include whole-body cold water immersion (CWI), ice slurry ingestion, pre-prepared ice packs, evaporative techniques or a combination thereof. In contrast, early cooling for post-ROSC patients is difficult pre-admission to hospital due to equipment portability and effectiveness, while the precise core body temperature to be targeted for temperature management remains controversial.