Professor Adrian Bone
Professor of Cell & Molecular Biology
Pharmacy and Biomolecular Sciences
I am Professor of Cell & Molecular Biology and Head of the Diabetes Research Group at the University of Brighton. I obtained my DPhil at the University of Sussex studying regulation of insulin production in pregnancy and starvation. I was then awarded a two year Wellcome Trust Travelling Research Fellowship to Europe held at the Biomedicum Centre in Uppsala, Sweden. I then returned to take up a Senior Research Fellowship in the Medical School at the University of Newcastle upon Tyne.
After three years in Newcastle I moved to Edinburgh and worked for the NHS as a Senior Grade Clinical Biochemist for five years. I subsequently took up the post of Senior Lecturer in Molecular Endocrinology in the Department of Medicine at the University of Southampton. I was then awarded my current Chair by the University of Brighton in 1992. I have been a career scientist for almost 40 years working across a broad range of biological and clinical areas and disciplines (>120 peer reviewed articles with >2100 citations in high impact international journals). A particular focus, drawing on my expertise in immunology, biotechnology and regenerative medicine, continues to be the prevention and treatment of diabetes and its long-term complications.
Since 1982, I have supervised a total of 2 MPhil and 22 PhD students to completion:
- University of Edinburgh: (Walker, Tames, Foggensteiner, Cole): Principal Supervisor, 4 PhDs
- University of Southampton: (Francis, Zhang, Bannister, Davies): Principal supervisor, 4 PhDs
- University of Brighton (Lally, Hitchcock, Stickings, Sigfrid, Rosales-Hernandez, Macdonald, Landy, Bockhart, Barry, Kumar, Alhasawi): 11 PhDs
- University of Uppsala, (Swenne), External Supervisor, 1 PhD
- University of Exeter (Willcox, Leete): External supervisor, 2 PhDs
|Current Phd Students|
|Jody Lucas (2012 – 2016)
||The lived experience of active Charcot foot in Diabetes Mellitus – Identifying ways to improve patient care
|Madeleine Honey (2016 – 2020)
||What is the mechanism through which antipsychotics cause Metabolic Syndrome and influence beta-cell toxicity.
|Victoria Odore (2016 – 2020)
||Continuous Glucose Monitoring Systems (CGMS) as a motivational tool in young obese individuals
|Elaine Sharp (2016 – 2020)
||The role of time-perspective in adherence and self-care among young type 1 diabetes patients.
Research collaboration coordination and leadership - International
- Steering Committee Member – EU Commission BIOMED 2 Concerted Action Programme. Islet Research European Network (IREN). (18 Partners; May 1998 – May 2002)
- Workpackage Leader/UK Regional Coordinator – Coordination Action on the aetiology, pathology and prediction of type 1 diabetes in Europe (Project acronym: TONECA). EU Sixth Framework Programme Priority 1.1.1: Life Sciences, Genomics & Biotechnology for Health. (28 Partners: May 2004 – May 2008)
- Workpackage Leader – EU NEXT Collaborative Project to develop nano-engineered, Immune-shielded pancreatic islets for transplantation into non systemically immune-suppressed diabetic patients. EU FP7-HEALTH-2013-INNOVATION-1. (4 Partners: September 2013 - September 2016)
- Head – Focus Groups Workpackages 1 & 2; Chair Management Committee Workpackage 4 – EU Interreg 2 Seas Area – Project: Design of Enabling- Regenerative Materials (Project acronym: DERMA) (4 Partners – UoB Lead: September 2016 – December 2019)
Expert/Peer-Review Groups - International
- Expert Panel Member EU 6th & 7th Research Framework Programme. Appointed 2002
- Expert/Rapporteur for the Marie Curie Individual Fellowships of the Human Resources and Mobility (HRM) Programme. Appointed 2005 – ongoing.
- Expert Reviewer for PRTLI-funded Centre Impact Assessment. Higher Education Authority of Ireland. Appointed 2004.
- Review Committee/Site Visit Chair for Joint Centre/Programme Grant funded between Netherlands Organization for Health Research and Development (ZonMW), Dutch Diabetes Research Foundation (Diabetes Fonds) and JDRF (Juvenile Diabetes Research Foundation International). Leiden April 2007.
- Independent Expert for Health, Demographic Changes and Wellbeing for Horizon 2020 – the Framework Programme for Research and Innovation. 2014 – ongoing
- Independent Expert, Evaluation Panel Member and Rapporteur – Innovative Medicines Initiative 2 ( www.imi.europa.eu ); European Federation of Pharmaceutical Industries and Associations ( www.efpia.eu ). 2014 – ongoing
Expert Peer Review Groups – National
- Member of the Royal Pharmaceutical Society’s Panel of Experts in the Pharmaceutical Sciences. Elected 1997 - ongoing.
- Member of the British Endocrine Societies Liaison Committee and Programme Organising Committee for BES meetings (BDA/Diabetes UK Representative). Elected 1997.
- Honorary Secretary of the Medical and Scientific Section of BDA (Subsequently Diabetes UK). 1997 – 4yr term.
- Programme and Organising Committee for the Annual Professional Sections Conference of Diabetes UK – Glasgow 1999, Brighton 2000 (Committee Chairman), & Birmingham 2002.
- Member of the Medical and Medical & Social Research Advisory Panels for the National Lottery Charities Board (Community Fund). Appointed 2003.
- Chairman of Programme/Local Organising Committee for the joint British Endocrine Societies/European Federation of Endocrine Societies Conference - Brighton 2004
- Member of the UK Advisory Council and Professional Advisory Council Executive of Diabetes UK. Elected 2005 – ongoing
- Chair of the Science & Research Section of Diabetes UK. Elected 2004 – 2008
- Chairman – RD Lawrence Fellowship Committee, Diabetes UK. Appointed 2007.
- Scientific Advisory Committee Member UK Islet Transplant Consortium. Appointed 2008 - ongoing
- Independent Member of the Ministry of Defence Independent Scientific and Technical Advice Register (ISTA) to provide independent advice to the Secretary of State for Defence on non-nuclear Science, Engineering, Technology, and Analysis (SETA) issues. Appointed February 2012 for a 3 Yr. term – renewed 2015 until 2018
- Convener and Co-Chair to develop “Type 1 Diabetes Research Agenda & Roadmap for the UK” to identify international Type 1 diabetes research priorities and set research agendas for both UK and European research teams. Juvenile Diabetes Research Foundation International. UK Parliamentary Launch, House of Commons, June 12th 2013.
- Panel Member National Centre for the Replacement Refinement & Reduction of Animals in Research – NC3Rs. Appointed 2015 – ongoing
- Independent Expert Panel Member – Chemical & Biological – MOD Science Capability Review to assess the strength and function of current UK Science & Technology capability and capacity. Appointed Dec 2014 – ongoing. Final Classified Report – A Review of MOD’s Science & Technology Capability released March 2015.
- Invited Expert Reviewer – External Red Team Review of UK Future Chemical Biological Science & Technology Capability – January 2016
Major Committees and Strategic Policy Groups: University of Brighton
- Chair of Research Management Group/Head of Research – School of Pharmacy (subsequently Pharmacy & Biomolecular Sciences). 1992 – 2010
- Chair of Faculty of Health Research Strategy Committee. Schools of: Pharmacy; Physiotherapy; Podiatry; Nursing & Midwifery; Health and Social Policy. 1992 – 1998.
- Chair of Faculty of Science and Engineering Research Strategy Committee. Schools of Engineering, Environment and Pharmacy & Biomolecular Sciences.1998 – 2007
- UoB Representative (with House, Whiting, Denyer) on the Medical School Working Group – 1998. Successful bid led to establishment of the Brighton & Sussex Medical School – opened in 2003/4
- RAE Leader: Research Assessment Exercise ‘96. Unit of Assessment for School of Pharmacy, University of Brighton. Unit of Assessment 9 - Rating of 3b awarded Dec ‘96
- RAE Leader: Research Assessment Exercise 2001. Unit of Assessment for School of Pharmacy & Biomolecular Sciences. Unit of Assessment 11. Rating of 5 awarded Dec 2001.
- RAE Leader: Research Assessment Exercise 2008. Unit of Assessment for School of Pharmacy & Biomolecular Sciences. Unit of Assessment 12a.
- Member of University Research Strategy Group. 1996 - 2010
- Member and subsequently Chair of University of Brighton Research Degrees Committee. 1998 – 2007
- Member of University of Brighton Research Marketing & Development Strategy Advisory Group. 2011
- Director of Research Development – Faculty of Science & Engineering. 2010 - 2011
- Faculty of Science & Engineering Representative on Brighton & Sussex Medical School Academic Board. 2010 – 2015
- University of Brighton Home Office Liaison Officer; Named Training & Competency Officer; Member – Animal Welfare & Ethics Review Board (AWERB) 2010 – ongoing
- University of Brighton Doctoral College Falmer Site Committee member. 2013 – ongoing
- School of Pharmacy & Biomolecular Sciences Athena Swan Steering Group Member. 2013 – ongoing
- University of Brighton Research Leadership Programme Mentor. 2014 - ongoing
2008 - Diabetes UK Lifetime Achievement Award in recognition of outstanding contribution to the UK Advisory Council