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Centre for Stress and Age-Related Disease
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  • Chemical Biology

Chemical Biology

Our expertise spans the traditional areas of organic, inorganic, physical and analytical chemistry. Our chemists regularly work in partnership with our experts in biology, medicine, materials science, environmental science and nanotechnology. 

Our chemistry research encompasses organic synthesis, medicinal chemistry, analysis, electrochemistry, geochemistry, the chemistry of materials, computational chemistry, supramolecular chemistry, coordination chemistry, protein chemistry and sensors. Group members are prominent within academic, advisory, and policy bodies, including the Royal Society of Chemistry, and act on Research Council and EU panels and in peer-review and editorial roles at leading scientific journals.

Pillarenes-x-ray-and-data

Pillar(5)arenes

Pillar(5)arenes are being functionalised to be bound to surfaces and used as sensors for chemical species.

Sensopellet

SensoPellet

A new tool to investigate signalling and motility in the lower digestive tract.

Photorelease-live-dead-assay

PHOTORELEASE

Developing sugar-NDs as novel inhibitors for Escherichia coli-derived biofilm formation.

Faecal-sensor

Faecal sensor to understand how signalling and muscle dynamics alter with incontinence

GALK1

Galactosemia – protein misfolding diseases which result in cellular stress

NQO1-variants

Antioxidative enzymes - NQO1 – an enzyme which protects against stress

Probing-Ion-transport-mechanisms-graph

Probing ion transport mechanisms with synthetic ion channels

Computational-representation-of-CWAs

A computational protocol to model organophosph(on)ate chemical warfare agents and their simulants

Molecular-structure-of-the-metal-radical-cation

Switchable molecules: a radical approach

Box one imageMagnetic-drug-delivery-diagram Switchable surfactants in drug delivery
Box two imageSmall-angle-x-ray-diffractogram-final

Quantifying a biophysical model of lipid-protein

Lipid-DNA interactions in crowded molecular environments

Box 3 imageDDM-lipid-homeostasis

Modelling of the mechanisms of phospholipid homeostasis

Adopting A tandem computational and experimental strategy to address a long-standing biological question.

STRAND-resveratrol

Synthesis and evaluation of Resveratrol derivatives

STRAND-ageing-cells

Identifying small molecules to remove or modify the phenotype of ageing cells

Skull

Sex determination of human remains from peptides in tooth enamel

RESEARCHER TEAM

Dr Peter J Cragg 
Dr Marcus Dymond 
Dr Ian Gass   
Dr Lizzy Ostler 
Dr Bhavik Anil Patel
Dr Nicolas Stewart

POSTGRADUATE RESEARCHERS

Joshua Eardley
Blaise Geoghegan
Megi Kamenica
Charis Nathan
Martin Osborne
Shaimaa Shakargi
Elaheh Sirjani

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