• Skip to content
  • Skip to footer
  • Accessibility options
University of Brighton
  • About us
  • Business and
    employers
  • Alumni and
    supporters
  • For
    students
  • For
    staff
  • Accessibility
    options
Open menu
Home
Home
  • Close
  • Study here
    • Meet us
    • Open days and visits
    • Virtual tours
    • Upcoming events
    • Meet us in your country
    • Chat to our students
    • Ask us a question
    • Order a prospectus
    • Our campuses
    • Our four campuses
    • Accommodation options
    • Our halls
    • Helping you find a home
    • What you can study
    • Find a course
    • Full A-Z course list
    • Explore our subjects
    • Our academic departments
    • How to study with us
    • Applying through Clearing
    • Undergraduate application process
    • Postgraduate application process
    • International student application process
    • Apprenticeships
    • Transfer from another university
    • Fees and financial support
    • Undergraduate finance
    • Postgraduate finance
    • Our funding and support options
    • Supporting you
    • Your wellbeing
    • Student support and guidance tutors
    • Study skills support
    • Careers and employability
  • Research
    • Research and knowledge exchange
    • Research and knowledge exchange organisation
    • The Global Challenges
    • Centres of Research Excellence (COREs)
    • Research Excellence Groups (REGs)
    • Our research database
    • Information for business
    • Community University Partnership Programme (CUPP)
    • Postgraduate research degrees
    • PhD research disciplines and programmes
    • PhD funding opportunities and studentships
    • How to apply for your PhD
    • Research environment
    • Investing in research careers
    • Strategic plan
    • Research concordat
    • News, events, publications and films
    • Featured research and knowledge exchange projects
    • Research and knowledge exchange news
    • Inaugural lectures
    • Research and knowledge exchange publications and films
    • Academic staff search
  • About us
  • Business and employers
  • Alumni, supporters and giving
  • Current students
  • Staff
  • Accessibility
Search our site
Strand-banner-image
Centre for Stress and Age-Related Disease
  • What we do
  • Join us
  • Who we are
  • What we do
    • What we do
    • Cell biology
    • Chemical biology
    • Our research and enterprise impact
    • Our research and enterprise projects
    • Translational sciences
  • Our research and enterprise projects
    • Our research and enterprise projects
    • A computational protocol to model organophosphonate CWAs and their simulants
    • A reactive oxygen and nitrogen species monitoring system to study their role in cancer
    • Amphiphilic-polymer-based-enhancers-for-local-drugs-delivery-to-the-inner-ear
    • Antibiotic efficacy in treating wound infection
    • Antioxidative enzymes
    • BK channels as Pharmacological targets for therapeutic intervention
    • Clinically reflective cellular model systems for Type 1 diabetes
    • Combating disorders of CNS myelination
    • Controlling infection in urinary catheters
    • C-Stress project
    • Development of a novel platform for local targeted treatment of cardiovascular disease
    • Development of an infection detecting wound dressing
    • Effects of age on signalling and function in the lower bowel
    • Effects of age on the central nervous system
    • Electrochemical sensor devices to understand ageing and disease mechanisms
    • Exploiting genomics to understand the role of vitamin D in human health and metabolism
    • Exploring the role of ADRB2 in triple negative breast cancer
    • Faecal sensor
    • Galactosemia – protein misfolding diseases which result in cellular stress
    • Hepatic disease
    • HIIT for Health
    • Identifying small molecules to remove or modify the phenotype of ageing cells
    • Increasing insulin production
    • Infection detecting wound dressing
    • Inflammation and Immunity
    • Modelling of cellular phospholipid homeostasis
    • Novel explanation for NSAID-induced cardiovascular side effects
    • organ of Corti
    • Pancreatic islet cell replacement and transplantation
    • PHOTORELEASE
    • Pillar(5)arenes
    • PPARβδ control of inflammation
    • Probing ion transport mechanisms with synthetic ion channels
    • Proteomic and genomic analysis of cellular stress responses
    • Quantifying-a-biophysical-model-of-lipid-protein
    • SensoPellet
    • Sex determination of human remains from peptides in tooth enamel
    • Stress hormones in BRCA mutation carriers
    • Switchable Molecules: A Radical Approach
    • Switchable surfactants in drug delivery
    • Synthesis and evaluation of Resveratrol derivatives
    • The effects of pre-natal alcohol on adolescent learning and memory
    • Translational regulation of stress responses and antibiotic production in Streptomyces bacteria
    • Type 1 Diabetes – cause and cure
    • Type 2 Diabetes
    • Understanding how social isolation increases morbidity and mortality
  • Understanding how social isolation increases morbidity and mortality

Understanding how social isolation increases morbidity and mortality

Lifespan in the UK is increasing. Studies by Independent Age, International Longevity Centre-UK and English Longitudinal Study of Ageing have shown that 15 per cent of older men and 11 per cent of women experience moderate to severe loneliness. Social isolation in older people increases morbidity and premature death and is as detrimental to health as smoking, obesity and a sedentary lifestyle. Specifically, social isolation stress can lead to depression in older people and has also been shown to have effects on learning and memory. Despite the impact that social isolation has on health, the underlying mechanisms that drive the increase in morbidity and mortality are not completely understood.

Project timeframes

The project began in 2014 and is ongoing.

 

Project aims

The project aimed

  • to utilise pre-clinical models to understand more about the relationship between the ageing process, social isolation stress and health.
  • to utilise these findings to improve the interventions that are available to older socially isolated people to increase quality of life and independence in older people.

Project findings and impact

Through an understanding of the mechanisms by which social isolation increases morbidity and mortality we hope to be able to deliver better interventions to improve the health of older people.

Research team

Dr Mark Yeoman

Dr Melanie Flint

Dr Bhavik Patel

Dr Lucy Redhead

Dr Chris Cocking

Dr Caroline Garrett

Railton Scott

Anna Blunden

Output

This project has just started in the Department but has gained funding through the Community University Partnership Programme.

Partners

Age Concern, Eastbourne

Dr Jerome Swinny, University of Portsmouth.
Back to top
  • Facebook
  • Twitter
  • Instagram
  • TikTok
  • YouTube
  • LinkedIn icon

Contact us

University of Brighton
Mithras House
Lewes Road
Brighton
BN2 4AT

Main switchboard 01273 600900

Course enquiries

Sign up for updates

University contacts

Report a problem with this page

Quick links Quick links

  • Courses
  • Open days
  • Order a prospectus
  • Academic departments
  • Academic staff
  • Professional services departments
  • Jobs
  • Privacy and cookie policy
  • Accessibility statement
  • Libraries
  • Term dates
  • Maps
  • Graduation
  • Site information
  • Online shop
  • COVID-19
  • The Student Contract

Information for Information for

  • Current students
  • International students
  • Media/press
  • Careers advisers/teachers
  • Parents/carers
  • Business/employers
  • Alumni/supporters
  • Suppliers
  • Local residents