Dr. Flint is a Reader in Cancer Research at the University of Brighton. She is currently Co-leader of Brighton and Sussex Cancer Research Network and a member of the Cancer Translation Advisory Group Steering Committee and Theme leader for Cancer. Dr. Flint is also a member of the NCRI Symptom Management Working Group.
Dr. Flint trained in the Women’s Cancer Research Center, at the University of Pittsburgh cancer Institute and remains at adjunct Research Assistant Professor in the Department of Pharmacology, University of Pittsburgh.
Her work on the effect of stress on cancer progression, chemotherapy and the immune system has been highlighted in the Making Research Matter and will likely results in changing treatment paradigms in patients with cancer.
How I like to teach
I currently teach Immunopharmacology, autoimmunity and I’m case leader for Breast Cancer. I prefer a more hands on practical approach to my teaching—this can be achieved though interactive lectures and workshops. Together with psychologist, Macmillan nurses, pharmacologists and pharmacists we will create interactive workshops to enhance student experiences.
Its very exciting to work on a (series) of projects that combine the expertise of laboratory based scientists with that of psycho-oncologists in an innovative area of research likely to produce tangible benefits for patients receiving cancer treatments. Valerie Jenkins, SHORE-C Sussex health Outcomes Research and Education group.
Currently, the focus of my laboratory is translational cancer research. Specifically, my research examines hormonal influences on cell cycle regulation and cancer. My primary research project involves the direct interplay between stress hormones (cortisol, noradrenaline) and the immune and cancer cells. This is accomplished through a mechanistic study of administration of stress hormones to cancerous cells, and observing these effects both in vitro, in vivo and human tissue sample models. The goal of my laboratory is to understand the mechanism through which behavioural stress impacts cancer progression.
PI Externally Funded Projects
Team Verrico 'Exploring polymorphisms in breast cancer' June 2018-2017 £15,000.
CRUK 'A reactive oxygen and nitrogen species (ROS/RNS) monitoring system to study their role in cancer' Role: Co-Principal Investigator Jan 2018-Jan 2020.
Breast Cancer Research Trust 'Stress hormones in BRCA mutation carriers increase susceptibility to the development of breast cancer' £49,997 Dec 2017-Dec 2018
I received my Ph.D. at Imperial College, London, UK. I moved to the United States and trained as a postdoctoral scientist at the National Institute of Occupational Safety and Health, Morgantown, WV. It was there that I began a research track in the field of biobehavioral research. I became very interested in the power of stressful influences impacting disease outcome. At the time, I remained focused on the immune and inflammatory systems and the impact of stressful responses. My research interests began to include investigations into how psychosocial hormones influence the immune system and may impact cancer biology. Indeed, I was recruited to join the Behavioral Oncology team at the University of Pittsburgh Cancer Institute (UPCI) as a Research Associate on the basis of my past experience in the field of stress and the immune system. During my tenure in this group, I worked on a number of projects related to how stress may impact the incidence and course of cancer, with a focus on the impact of stress and stress hormones on DNA damage and repair. In 2007, I was promoted to Research Instructor in the Department of Pharmacology & Chemical Biology. I began to apply my molecular and cell biology expertise to complement my breast cancer research, especially with the validation and implementation of cancer biomarkers. I became a Research Assistant Professor in 2012, where I trained in breast and ovarian cancer at the Womens cancer Research center, Pittsburgh. I am currently a Senior lecturer and leader of a stress and breast cancer program at the University of Brighton.
Marta Falcinelli Oct 2016-Oct 2019
Haya Intablis Jan 2016-Dec 2019
Maysa Maysa Al-Natsheh Jan 2017-Jan 2020
Gheed Alhity Jan 2019-Dec 2021
Post Doctoral Scientists (as of 2018)
Dr Aya Abdullah
Dr Renee Flaherty
Dr Caroline Garrett
Dr Will Jones