- From London: the M25/M23 link provides road access from London and the rest of the country.
- From east and west: the A27 and the A259 provide access to Brighton. The A259 runs along Brighton seafront.
For Moulsecoomb, Grand Parade and Varley Park from the A27 eastbound take the slip road towards Hollingbury, go straight over the roundabout then down Coldean Lane. There are signs to the University of Brighton at the bottom of Coldean Lane.
For Falmer stay on the A27 eastbound until you see the signs to the University of Brighton.
From the west there are signs to the University of Brighton before and after Falmer bridge on the A270.
- National Express coaches depart for Brighton from London Victoria coach station 18 times a day.