Regenerative Medicine and Devices MRes

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Course structure

The Regenerative Medicine and Devices MRes is typically completed full-time in one year, but can be taken part-time over two years. The course is structured to include a significant research component which you will undertake throughout the course. In addition, supporting taught modules further enrich your learning.

You will further deepen your understanding of the wider research community and literature through our specialist journal clubs with seminars from expert speakers as well as more informal, student-led presentations. And you will develop your practical, lab-based skills using our specialist facilities and equipment, supported by our technical team.

To be awarded the MRes, you must obtain 180 M-level credits, 40 credits from taught and subject-specific modules and 140 credits through the completion of the research project.

Syllabus

Modules

Core modules

• Regenerative Medicine and Medical Devices

  Regenerative Medicine and Medical Devices will introduce you to the field of regenerative medicine, medical implants and diagnostics. Areas covered include conventional medical implants and devices and personalised regenerative medicine approaches in cell-based therapy, gene therapy and tissue engineering. You will explore the factors influencing biocompatibility of materials in relation to specific clinical applications and expanded to conventional implants, cell carriers and nanobiomaterials as vectors/carriers for genes and drugs.

• Evaluating Research in Biosciences

  Evaluating Research in Biosciences will give you a critical understanding of innovative developments in biosciences and enable you to study a topic of current bioscience research in depth. Delivered via a series of presentations by university staff, external speakers and students, the module also includes seminars where you will take a leading role in facilitating and discussing material. You will be expected to evidence your literature research with a portfolio of annotated research articles.

• MRes Research Project

  During this module you will carry out a detailed independent investigative research project within a relevant academic discipline, field of study or area of professional practice. You will develop advanced skills in project planning, data generation and analysis, critical analysis of scientific literature, and written and oral presentation to the expected level of a professional scientist.

Options*

• Applied Nucleic Acid Biochemistry

  This module provides you with an understanding of modern nucleic acid-based techniques and how these can be applied in the laboratory with respect to human disease. You will study basic molecular biology techniques including cloning into simple vectors, gene expression and selectable markers, and learn about manipulation and detection of nucleic acid and protein and the concepts and applications of genomics and bioinformatics. You will also undertake a mini project.

• Clinical Microbiology in the Post-Antimicrobial Era

  Clinical Microbiology in the Post-Antimicrobial Era will cover the complex factors influencing microbial pathogenesis, the clinical presentation of infectious disease and microbial resistance to antibiotics. You will explore aspects of infection management practice and the use of rapid diagnostic methods to accelerate appropriate treatment of infection. You will also learn to critically evaluate current thinking regarding organism and host factors which affect pathogenesis of infectious agents.

• Oxidative Stress and Human Disease

  This module highlights the role of oxidative stress in normal human physiology and in the development of conditions and diseases. You will examine the basic biochemical mechanisms involved in oxidative stress and injury and discover how the human body can protect itself against this. You will also explore the development of pharmacological interventions which have the potential to reduce oxidant injury, for example antioxidant enzyme mimetics and oxidant injury pathway inhibitors.

• Monitoring Signalling Molecules in Neuroscience

  This module provides you with an overview of signalling mechanisms and how they may be altered through pharmacological intervention, ageing and disease. You will explore the theory, capabilities, limitations and applications of the techniques used in monitoring signalling molecules in vivo and in vitro, including amperometry, fast scan cyclic voltammetry and microdialysis. You will also learn to understand, interpret and critically evaluate the latest scientific literature in this field.

• Ageing: Pathology and Prevention

  This module will explain the current understanding of the causes and features of the degenerative pathology associated with ageing. You will look at the fundamental biology of ageing and the physiological changes that occur with age, for example regarding tissue function and bone density. You will also explore the application, discovery and development of interventions to promote healthy ageing, including lifestyle, nutrition and supplementation.

• Cancer: Bench to Bedside

  This module provides you with an overview of the fundamental biological processes underlying cancer and develops your knowledge of the treatment possibilities provided by our understanding of how cancer works at a biological level. You will cover areas such as risk factors and diagnosis, radiotherapies, immune therapies, psychosocial oncology and in vivo and in vitro cancer models, and get an insight into the journey from diagnosis to treatment to remission.

• Understanding Age-Related CNS Disorders

  This module will provide you with an insight into current research aimed at understanding the mechanisms that drive CNS ageing and Alzheimer’s and Parkinson’s disease. Through discussing primary scientific literature, you will develop an understanding of the future targets for treating a range of CNS diseases, be able to critically evaluate the potential clinical uses of these targets and develop the necessary skills to critique the literature.

• Controversies in Science

  Controversies in Science will develop your ability to critically review and understand the nature of progress in science. A series of case studies from different disciplines and time periods will illustrate how scientific theories develop and why, by their nature, scientific hypotheses are always formulated in an environment of initially contradictory evidence. You will select a controversial area of modern science, review the competing theories to find the key drivers of disagreement and suggest experimental or theoretical means by which these might be resolved.

• Omics for Diseases: Theory, Practice and Applications

  This module covers the theory, practice and application of omics at the genomic, proteomic and metabolomic level. You will learn about the types of omics currently on the market and the use of omics technologies in basic research, medicine and pharmaceutical sciences for diagnosis, prognosis and treatment of diseases. You will gain hands-on experience with genomics and proteomics datasets and at the end of the module present a poster discussing recent advances in omics.

• Applied Protein Biochemistry

  Involving a mini project, this module provides you with a theoretical and practical understanding of how modern techniques in the fields of protein production and analysis can be applied in a variety of laboratory settings. You will look at recombinant protein induction and purification techniques, including sonication and metal ion-agarose affinity column use, as well as the analysis of proteins by SDS-PAGE and Bradford assays for protein concentration. You will also study spectrophotometric assays of activity in normal and mutant proteins.

• Nanotechnology Research: Therapeutics, Diagnostics and Advanced Pharmaceutics

  This module focuses on contemporary and innovative research in the nanotechnology field, including nanoparticle drug delivery systems, medical diagnostics and molecular therapeutic agents. The content covers pharmaceutical sciences, pharmacology, microbiology, molecular biology and clinical diagnosis. With an emphasis on modern practical techniques and methodologies, the module will provide you with specialised knowledge of the use and role of both established and novel nanotechnologies in modern therapy.

• Novel Medicinal Products: A Clinical Perspective

  In this module you will demonstrate a sound understanding of the multidisciplinary framework of research and development. You will develop an understanding of the processes involved in developing new drug substances and products as well as the pre-clinical and clinical trial protocol to optimise patient safety for new medications. You will also show an understanding of the regulatory processes and controls in place during and after drug development.

• Industrial Manufacturing Processes

  This module enables you to demonstrate a sound understanding of the production, testing, distribution and regulatory aspects of medicine production in the pharmaceutical industry and meet the demand for capable pharmacy graduates who can contribute to the continued growth and development of the pharmaceutical industry. The module includes 18 hours of placement in an industrial setting.

*Option modules are indicative and may change, depending on timetabling and staff availability.

Staff profile

Professor Matteo Santin

Professor Santin is Professor of Tissue Regeneration in the School of Applied Sciences and the Director of the Centre for Regenerative Medicine and Devices.

Professor Santin's research interests are in the field of regenerative medicine. He has been involved in many research projects with a focus on bone and cartilage regeneration, cardiovascular devices, control of angiogenesis in cartilage regeneration and ischaemia and neurodegenerative diseases.

He is also academic lead for Healthy Futures, one of five themes for cross-cutting research and enterprise across the university. He has over 25 years’ experience in the field of Biomaterials for Medical Devices and Tissue Engineering for a wide range of clinical applications. He has founded two start-up companies: Tissue Click Ltd and Brighton Wound Care Ltd.

Find out more about the team here.

Facilities 

Our specialist facilities include:

• clinical simulation environment 
• dedicated genomics/metabolomics/proteomics facility 
• imaging and analysis unit (including both electron and confocal microscopy)
• extensive cell and tissue culture facilities
• human movement laboratory
• clinical imaging sciences centre
• high-performance liquid and gas chromatography, atomic emission, UV/Vis and IR spectroscopy
• nuclear magnetic resonance (NMR) and mass spectrometry
• modern synthetic and analytical chemistry equipment
• a range of specialist research equipment (for use in projects), including electrophysiology rigs, a FACS machine and a dedicated histology lab.

Click to view a virtual tour of some of our biosciences facilities.

Course fees

Scholarships, bursaries and loans

We offer a range of scholarships for postgraduate students. Bursaries and loans may also be available to you.

Find out more about postgraduate fees and funding.

The fees listed here are for the first year of full-time study if you start your course in the academic year 2025–26.

You will pay fees for each year of your course. Some fees may increase each year.

UK undergraduate and some postgraduate fees are regulated by the UK government and increases will not be more than the maximum amount allowed. Course fees that are not regulated may increase each year by up to 5% or RPI (whichever is higher).

If you are studying part-time your fee will usually be calculated based on the number of modules that you take.

Find out more

• Fees, bursaries, scholarships and government funding info for UK and international postgraduate students
• Student finance and budgeting while studying
• About the university’s fees by checking our student contract and tuition fee policy (pdf).

Campus where this course is taught

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